Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.39 |
| ▸ | WNT3A | P56704 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18308447 | 0.88 | PLK1 (0.48) | KDM4EALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL11267151 | 0.76 | ALDH1A1 (0.41) | KDM4EALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL15988852 | 0.75 | PLK1 (0.49) | KDM4EALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL30330021 | 0.74 | PLK1 (0.71) | KDM4EALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL6995732 | 0.74 | PLK1 (0.71) | KDM4EALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL1278933 | 0.71 | SMN1; SMN2 (0.53) | KDM4EALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL24328780 | 0.71 | MAPT (0.42) | KDM4EALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL27432422 | 0.71 | ALDH1A1 (0.49) | KDM4EALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL15988858 | 0.70 | PLK1 (0.45) | KDM4EALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL9110788 | 0.70 | ALDH1A1 (0.51) | KDM4EALDH1A1POLBTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016199943-A1 | HETEROCYCLIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-12-15 | — | — | WO | disclosed |