Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ANPEP | P15144 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.46 |
| ▸ | LAP3 | P28838 | 2/20 | 0.45 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.45 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6045130 | 0.81 | KMT2A (0.79) | KMT2AALDH1A1HPGDANPEPPOLB | |
| Hydrochloric Acid SCHEMBL10725331 | 0.81 | TAS1R3 (0.47) | KMT2AALDH1A1LMNAPKMTAAR1 | |
| Hydrochloric Acid SCHEMBL10725329 | 0.81 | TAS1R3 (0.47) | KMT2AALDH1A1LMNAPKMTAAR1 | |
| SCHEMBL2013100 | 0.80 | KMT2A (0.57) | KMT2AALDH1A1HPGDANPEPPOLB | |
| SCHEMBL5907625 | 0.80 | KMT2A (0.63) | KMT2AALDH1A1HPGDPOLBLMNA | |
| SCHEMBL10764126 | 0.79 | HPGD (0.57) | ALDH1A1HPGDLMNAPKMHDAC1 | |
| SCHEMBL4186748 | 0.79 | KMT2A (0.56) | KMT2AALDH1A1HPGDANPEPPOLB | |
| SCHEMBL10148117 | 0.79 | NPC1 (0.54) | KMT2AALDH1A1ANPEPLMNATAAR1 | |
| SCHEMBL4184855 | 0.79 | KMT2A (0.56) | KMT2AALDH1A1HPGDANPEPPOLB | |
| SCHEMBL18426210 | 0.78 | KMT2A (0.58) | KMT2AALDH1A1HPGDANPEPPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016197190-A1 | STRUCTURE OF PLASMEPSIN V IN COMPLEX WITH AN INHIBITOR AND USES THEREOF | THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) | 2016-12-15 | — | — | WO | disclosed |