Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | ANPEP | P15144 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4184855 | 1.00 | KMT2A (0.56) | KMT2AHPGDALDH1A1POLBANPEP | |
| SCHEMBL18426210 | 0.89 | KMT2A (0.58) | KMT2AHPGDALDH1A1POLBANPEP | |
| SCHEMBL2013100 | 0.88 | KMT2A (0.57) | KMT2AHPGDALDH1A1POLBANPEP | |
| SCHEMBL338918 | 0.86 | MMP8 (0.54) | KMT2AHPGDALDH1A1ANPEPMEN1 | |
| SCHEMBL2014475 | 0.83 | HDAC3 (0.55) | KMT2AHPGDALDH1A1POLBANPEP | |
| Phenethylamine SCHEMBL31288496 | 0.82 | HTR2A (0.48) | KMT2AHPGDALDH1A1ANPEPTAAR1 | |
| SCHEMBL6045130 | 0.81 | KMT2A (0.79) | KMT2AHPGDALDH1A1POLBANPEP | |
| SCHEMBL4191585 | 0.81 | HPGD (0.52) | KMT2AHPGDALDH1A1POLBANPEP | |
| SCHEMBL29072420 | 0.81 | ANPEP (0.43) | KMT2AHPGDALDH1A1ANPEPMEN1 | |
| SCHEMBL18310372 | 0.79 | KMT2A (0.56) | KMT2AHPGDALDH1A1POLBANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2021318-A2 | SYNTHESIS OF (S)-(+)-3-(AMINOMETHYL)-5-METHYL HEXANOIC ACID | Teva Pharmaceutical Industries Ltd. (IL) | 2009-02-11 | — | — | EP | disclosed |
| WO-2008118427-A9 | SYNTHESIS OF (S)-(+)-3-(AMINOMETHYL)-5-METHYL HEXANOIC ACID | TEVA PHARMA (IL) | 2009-02-05 | — | — | WO | disclosed |
| WO-2008118427-A2 | SYNTHESIS OF (S)-(+)-3-(AMINOMETHYL)-5-METHYL HEXANOIC ACID | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2008-10-02 | — | — | WO | disclosed |