Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | WHR1 | P49842 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18455506 | 0.95 | MEN1 (0.45) | MEN1KMT2AATMNUDT1ADORA2A | |
| SCHEMBL18456129 | 0.93 | MEN1 (0.39) | MEN1KMT2AATMNUDT1ADORA2A | |
| SCHEMBL18456126 | 0.92 | MEN1 (0.39) | MEN1KMT2AATMNUDT1ADORA2A | |
| SCHEMBL18455508 | 0.92 | ATM (0.41) | MEN1KMT2AATMNUDT1ADORA2A | |
| SCHEMBL18456007 | 0.91 | MEN1 (0.43) | MEN1KMT2AATMNUDT1ADORA2A | |
| SCHEMBL22868898 | 0.91 | MEN1 (0.43) | MEN1KMT2AATMNUDT1ADORA2A | |
| SCHEMBL18455709 | 0.91 | MEN1 (0.52) | MEN1KMT2AATMNUDT1ADORA2A | |
| SCHEMBL21868326 | 0.91 | MEN1 (0.43) | MEN1KMT2AATMNUDT1ADORA2A | |
| SCHEMBL18455514 | 0.91 | MEN1 (0.46) | MEN1KMT2AATMNUDT1ADORA2A | |
| SCHEMBL18455710 | 0.90 | ATM (0.50) | MEN1KMT2AATMNUDT1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11208401-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2021-12-28 | — | — | US | disclosed |
| US-11201296-B2 | Compounds having fluorene structures | MERCK PATENT GMBH (DE) | 2021-12-14 | — | — | US | disclosed |
| US-11201296-B2 | Compounds having fluorene structures | MERCK PATENT GMBH (DE) | 2021-12-14 | — | — | US | disclosed |
| CN-107849016-B | Compound having fluorene structure | 默克专利有限公司 | 2021-10-22 | — | — | CN | disclosed |
| EP-3328850-B1 | COMPOUNDS HAVING FLUORENE STRUCTURES | MERCK PATENT GMBH (DE) | 2020-11-11 | — | — | EP | disclosed |
| EP-3328850-B1 | COMPOUNDS HAVING FLUORENE STRUCTURES | MERCK PATENT GMBH (DE) | 2020-11-11 | — | — | EP | disclosed |
| US-20180226587-A1 | COMPOUNDS HAVING FLUORENE STRUCTURES | MERCK PATENT GMBH (DE) | 2018-08-09 | — | — | US | disclosed |
| US-20180226587-A1 | COMPOUNDS HAVING FLUORENE STRUCTURES | MERCK PATENT GMBH (DE) | 2018-08-09 | — | — | US | disclosed |
| US-20180226587-A1 | COMPOUNDS HAVING FLUORENE STRUCTURES | MERCK PATENT GMBH (DE) | 2018-08-09 | — | — | US | disclosed |
| US-20180162843-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2018-06-14 | — | — | US | disclosed |
| US-20180162843-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2018-06-14 | — | — | US | disclosed |
| EP-3328850-A1 | COMPOUNDS HAVING FLUORENE STRUCTURES | Merck Patent GmbH (DE) | 2018-06-06 | — | — | EP | disclosed |
| WO-2017016667-A1 | COMPOUNDS HAVING FLUORENE STRUCTURES | MERCK PATENT GMBH (DE) | 2017-02-02 | — | — | WO | disclosed |
| WO-2017016667-A1 | COMPOUNDS HAVING FLUORENE STRUCTURES | MERCK PATENT GMBH (DE) | 2017-02-02 | — | — | WO | disclosed |
| WO-2016198144-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2016-12-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180226587-A1 | COMPOUNDS HAVING FLUORENE STRUCTURES | FSCN1, EFNA1, FLNA | MEN1 1658/4885KMT2A 2095/4885ATM 4239/4885 |
| US-11208401-B2 | Materials for organic electroluminescent devices | DDT, CELF2, BRD3 | MEN1 3573/4885KMT2A 2313/4885ATM 4330/4885 |
| US-11201296-B2 | Compounds having fluorene structures | FSCN1, EFNA1, FLNA | MEN1 1658/4885KMT2A 2095/4885ATM 4239/4885 |
| US-20180162843-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | DDT, CELF2, BRD3 | MEN1 3573/4885KMT2A 2313/4885ATM 4330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.