SCHEMBL18315980

SCHEMBL18315980

CCCCCCCCCCCCCC(=O)C(O)(C(=O)CCCCCCCCCCCCC)[C@@H](O)COP(=O)(O)OCCN

nearest known ligand 0.52

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PLA2G2C Q5R387 2/20 0.52
P2RY10 O00398 11/20 0.46
GPR34 Q9UPC5 5/20 0.46
GPR174 Q9BXC1 3/20 0.44
FABP3 P05413 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9957361 1.00 PLA2G2C (0.52) PLA2G2CP2RY10GPR34GPR174FABP3
SCHEMBL5968303 0.93 P2RY10 (0.52) P2RY10GPR34GPR174
SCHEMBL2011436 0.93 P2RY10 (0.52) P2RY10GPR34GPR174
SCHEMBL4752181 0.83 ENPP2 (0.56)
Phosphorylethanolamine SCHEMBL993264 0.83 LPAR3 (0.44) PLA2G2C
Phosphorylethanolamine SCHEMBL19412013 0.81 LPAR3 (0.42) PLA2G2C
SCHEMBL10594311 0.80 PLA2G2C (0.50) PLA2G2CP2RY10GPR34
SCHEMBL226745 0.77 PLA2G2C (0.43) PLA2G2CP2RY10GPR34GPR174
SCHEMBL3963403 0.77 PLA2G2C (0.43) PLA2G2CP2RY10GPR34GPR174
SCHEMBL19410782 0.77 PLA2G2C (0.43) PLA2G2CP2RY10GPR34GPR174

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160367638-A1 LEPTIN mRNA COMPOSITIONS AND FORMULATIONS BYERS CRYSTAL (US) 2016-12-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160367638-A1 LEPTIN mRNA COMPOSITIONS AND FORMULATIONS ADIPOR1, IGF2BP1, LRBA PLA2G2C 2709/4885P2RY10 4545/4885GPR34 3445/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.