IGF2BP1

Insulin-like growth factor 2 mRNA-binding protein 1 · Q9NZI8 · IGF2BP1 on Sugi Atlas →

254 patent compounds predicted against IGF2BP1, 223 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL24462168	0.62	3/20
Amarin (SCHEMBL231815)	1.00	2/20
Amarin (SCHEMBL10013358)	1.00	2/20
Amarin (SCHEMBL13668120)	1.00	2/20
Amarin (SCHEMBL17531553)	1.00	2/20
Amarin (SCHEMBL18177462)	1.00	2/20
Amarin (SCHEMBL19186443)	1.00	2/20
Amarin (SCHEMBL20121442)	1.00	2/20
Amarin (SCHEMBL22433345)	1.00	2/20
Cucurbitacin B (SCHEMBL29602393)	1.00	2/20
Amarin (SCHEMBL30863648)	0.98	2/20
SCHEMBL29459725	0.85	2/20
Cucurbitacin E (SCHEMBL29908892)	0.84	2/20
Cucurbitacin D (SCHEMBL230654)	0.82	2/20
Cucurbitacin D (SCHEMBL8166627)	0.82	2/20
SCHEMBL10307568	0.82	2/20
Cucurbitacin D (SCHEMBL20121444)	0.82	2/20
Cucurbitacin A (SCHEMBL10307352)	0.82	2/20
Cucurbitacin A (SCHEMBL20121493)	0.82	2/20
Cucurbitacin A (SCHEMBL22877821)	0.82	2/20

Clinical trials — most relevant to IGF2BP1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Metformin Use to Reduce Disparities in Newly Diagnosed Breast Cancer	PHASE4	WITHDRAWN
Insulin-like Growth Factor (IGF-I) in Hemodialysis Patients	PHASE4	COMPLETED
MK-0646 Insulin Growth Factor 1 Receptor Antibody in Stage IIIb or IV Metastatic Non-Squamous Lung Cancer	PHASE2	COMPLETED
Study Assessing Potential Predictive Tumor Markers in Metastatic Colorectal Cancer	PHASE2	COMPLETED
Defined Green Tea Catechins in Treating Patients With Prostate Cancer Undergoing Surgery to Remove the Prostate	PHASE1	COMPLETED
Pappalysin 2 (PAPP-A2) Enzyme Replacement	PHASE1	COMPLETED
Antisense102: Pilot Immunotherapy for Newly Diagnosed Malignant Glioma	PHASE1	COMPLETED
Phase 1 Study of the Effects of Combining Topical FDA-approved Drugs on Age-related Pathways on the Skin of Healthy Volunteers	PHASE1	COMPLETED
Prognostic Value of Protein IMP3 Expression in Cervical Cancer	nan	COMPLETED
The Association Between Diabetes Mellitus, Oral Lichen Planus and Insulin-like Growth Factors 1 and 2 (IGF1 and IGF2)	nan	COMPLETED
IGF and Other Neurotrophic Factors in Patients With Dementia	nan	COMPLETED
Nutrition and Lifestyle Changes in Patients With Previously Untreated Stage I or Stage II Prostate Cancer	nan	COMPLETED
Role of Biomarkers in Endometrial Cancer Recurrence in Samples From Patients With Stage II, Stage III, or Stage IV Endometrial Cancer	nan	UNKNOWN
Genetic Study of Insulin-Like Growth Factor-I Receptor Mutations in Patients With Intrauterine Growth Retardation	nan	UNKNOWN
Adipocytokines in Endometrial Cancer	nan	COMPLETED
Role of LncRNA H19 in The Regulation of IGF-1R Expression	nan	COMPLETED
Molecular Quantification of Insulin mRNA	nan	COMPLETED
Association of SNPs in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population	nan	COMPLETED
Advancing Early Bone Health: New Frontiers for Osteoporosis Prevention	nan	ACTIVE_NOT_RECRUITING
LINC00511/miR-185-3p Axis and miR-301a-3p Markers for Breast Cancer Diagnosis	nan	COMPLETED
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy	nan	UNKNOWN
Short-Term Fasting Before Chemotherapy in Treating Patients With Cancer	nan	COMPLETED
Metabolic and Inflammatory Responses to Hemodialysis and the Effect of a Meal	nan	COMPLETED
Assessment of the Diagnostic Role of Serum Insulin-like Growth Factor Binding Protein-3 as a Potential Biomarker for Colorectal Cancer (CRC) in Egypt	nan	NOT_YET_RECRUITING
MicroRNA-1 (miRNA-1) and MicroRNA-133a (miRNA-133a) Levels After Acute Exercise in Ultimate Frisbee Athletes	nan	UNKNOWN
Maternal Hypertriglyceridaemia Study	nan	UNKNOWN
Effect of AT-derived miRNA on the Biology and Insulin Sensitivity of Skeletal Muscle in Humans	nan	COMPLETED
Epigenetics and the Origin of Muscle Insulin Resistance in Humans	nan	COMPLETED
Emerging Role of NOTCH-related Long Non-coding RNA(s) as Biomarkers in Liquid Biopsy From Colorectal Cancer Patients	nan	COMPLETED
Epigenetics of Muscle Insulin Resistance	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a IGF2BP1 binder may also engage these)

Protein	Name	Similarity
Q8CGX0	—	1.000	Q8CGX0 →
O73932	—	1.000	O73932 →
O57526	—	1.000	O57526 →
IGF2BP2	Insulin-like growth factor 2 mRNA-binding protein 2	1.000	landscape →
O42254	—	1.000	O42254 →
IGF2BP3	Insulin-like growth factor 2 mRNA-binding protein 3	1.000	landscape →
O88477	—	1.000	O88477 →
Q5SF07	—	1.000	Q5SF07 →
Q5ZLP8	—	0.998	Q5ZLP8 →
Q08CK7	—	0.998	Q08CK7 →
Q9PW80	—	0.996	Q9PW80 →
Q5RB68	—	0.992	Q5RB68 →
Q9CPN8	—	0.991	Q9CPN8 →
Q9LZ82	—	0.981	Q9LZ82 →
P90978	—	0.978	P90978 →
C5DIR2	—	0.977	C5DIR2 →
Q9UKA9	—	0.976	Q9UKA9 →
Q29099	—	0.976	Q29099 →
Q54BM2	—	0.976	Q54BM2 →
Q66H20	—	0.976	Q66H20 →
Q756R8	—	0.975	Q756R8 →
Q8VDJ3	—	0.975	Q8VDJ3 →
P26369	—	0.975	P26369 →
Q6CDH3	—	0.975	Q6CDH3 →
Q4VXU2	—	0.975	Q4VXU2 →
Q5AI15	—	0.973	Q5AI15 →
PTBP3	Polypyrimidine tract-binding protein 3	0.973	landscape →
Q6DEY7	—	0.973	Q6DEY7 →
Q6FKG4	—	0.973	Q6FKG4 →
Q5R8F7	—	0.973	Q5R8F7 →