Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 18/20 | 0.72 |
| ▸ | HCAR3 | P49019 | 12/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3100973 | 0.84 | HCAR2 (1.00) | HCAR2HCAR3CYP1A2 | |
| SCHEMBL11294302 | 0.81 | HCAR2 (0.61) | HCAR2HCAR3CYP1A2 | |
| Hydrochloric Acid SCHEMBL11397838 | 0.81 | HCAR2 (0.60) | HCAR2HCAR3CYP1A2 | |
| Acifran SCHEMBL5055334 | 0.80 | HCAR2 (1.00) | HCAR2HCAR3CYP1A2 | |
| Acifran SCHEMBL188221 | 0.80 | HCAR2 (1.00) | HCAR2HCAR3CYP1A2 | |
| Acifran SCHEMBL11406401 | 0.78 | HCAR2 (0.78) | HCAR2HCAR3CYP1A2 | |
| Water SCHEMBL27728999 | 0.74 | NAPRT (0.96) | CYP1A2NAPRT | |
| Acifran SCHEMBL1876828 | 0.73 | HCAR2 (0.83) | HCAR2HCAR3CYP1A2 | |
| SCHEMBL48609 | 0.73 | NAPRT (1.00) | CYP1A2NAPRT | |
| SCHEMBL29430342 | 0.73 | NAPRT (1.00) | CYP1A2NAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160367623-A1 | AGONISTS OF GUANYLATE CYCLASE USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS, INFLAMMATION, CANCER AND OTHER DISORDERS | SYNERGY PHARMACEUTICALS INC. | 2016-12-22 | — | — | US | disclosed |