SCHEMBL18317166

SCHEMBL18317166

O=C(NCCCCCCCCCNC(=O)NCc1cccnc1)NCc1cccnc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FLT4 P35916 2/20 1.00
FES P07332 1/20 1.00
RET P07949 1/20 1.00
MARK3 P27448 1/20 1.00
TYK2 P29597 1/20 1.00
SYK P43405 1/20 1.00
CLK2 P49760 1/20 1.00
CLK4 Q9HAZ1 1/20 1.00
MAPT P10636 1/20 0.66
RECQL P46063 1/20 0.62
CDK2 P24941 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.61
CHRM2 P08172 1/20 0.59
NAMPT P43490 2/20 0.59
P2RX7 Q99572 1/20 0.59
CYP3A4 P08684 2/20 0.58
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
NPC1 O15118 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18317996 1.00 FLT4 (1.00) FLT4FESRETMARK3TYK2
SCHEMBL18317211 1.00 FLT4 (1.00) FLT4FESRETMARK3TYK2
SCHEMBL1514550 1.00 FLT4 (1.00) FLT4FESRETMARK3TYK2
SCHEMBL18317214 1.00 FLT4 (1.00) FLT4FESRETMARK3TYK2
SCHEMBL18317546 1.00 FLT4 (1.00) FLT4FESRETMARK3TYK2
SCHEMBL18317601 1.00 FLT4 (1.00) FLT4FESRETMARK3TYK2
SCHEMBL18317181 1.00 FLT4 (1.00) FLT4FESRETMARK3TYK2
SCHEMBL18334816 1.00 FLT4 (1.00) FLT4FESRETMARK3TYK2
SCHEMBL14323610 0.98 FLT4 (0.97) FLT4FESRETMARK3TYK2
SCHEMBL18327711 0.95 FES (0.91) FLT4FESRETMARK3TYK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016209785-A1 UREA GELLANTS THE PROCTER & GAMBLE COMPANY (US) 2016-12-29 WO claimed
EP-3109233-A1 UREA GELLANTS The Procter and Gamble Company (US) 2016-12-28 EP claimed
US-20160369208-A1 UREA GELLANT THE PROCTER & GAMBLE COMPANY 2016-12-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160369208-A1 UREA GELLANT UGP2, UGGT1, SLC14A1 FLT4 4174/4885FES 3050/4885RET 4422/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.