Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 1/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PPIB | P23284 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | TPH1 | P17752 | 2/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | CIT | O14578 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18180177 | 1.00 | BMP1 (0.41) | BMP1CLK1CLK2DYRK1AAAK1 | |
| SCHEMBL19999805 | 0.88 | MAOB (0.38) | ALDH1A1HTTMAOBCITPOLB | |
| SCHEMBL18179945 | 0.87 | PTPN1 (0.41) | MAOBCITSLC6A4DPP4DPP7 | |
| SCHEMBL29070723 | 0.85 | LDHA (0.43) | BMP1CLK1CLK2DYRK1AHSP90AA1 | |
| SCHEMBL18317595 | 0.85 | CIT (0.39) | ALDH1A1CITSMN1; SMN2 | |
| SCHEMBL18180281 | 0.85 | CIT (0.39) | AAK1ALDH1A1MAOBTPH1CIT | |
| SCHEMBL18180401 | 0.85 | CIT (0.39) | ALDH1A1CITSMN1; SMN2 | |
| SCHEMBL18181034 | 0.84 | AAK1 (0.42) | AAK1ALDH1A1HTTLDHA | |
| SCHEMBL19962106 | 0.84 | AAK1 (0.42) | AAK1ALDH1A1HTTLDHA | |
| SCHEMBL19999801 | 0.84 | CIT (0.41) | AAK1ALDH1A1MAOBTPH1CIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114456228-B | Substituted glycine-3, 5-difluorophenylalanine peptide derivative and preparation method and application thereof | 山东大学 | 2023-09-12 | — | — | CN | disclosed |
| CN-114456228-A | Substituted glycine-3, 5-difluorophenylalanine peptide derivative and preparation method and application thereof | 山东大学 | 2022-05-10 | — | — | CN | disclosed |
| EP-3286166-B1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV HEALTHCARE UK NO 5 LTD (GB) | 2020-05-13 | — | — | EP | disclosed |
| US-10202353-B2 | Therapeutic compounds | GILEAD SCIENCES, INC. (US) | 2019-02-12 | — | — | US | disclosed |
| US-20160368881-A1 | THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. | 2016-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160368881-A1 | THERAPEUTIC COMPOUNDS | HAVCR2, SARS1, RPL35 | BMP1 3514/4885CLK1 4333/4885CLK2 4161/4885 |
| US-10202353-B2 | Therapeutic compounds | RPL35, SARS1, HAVCR2 | BMP1 3578/4885CLK1 4361/4885CLK2 4162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.