Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17234876 | 0.87 | RBP4 (0.54) | RBP4 | |
| SCHEMBL30663898 | 0.85 | RBP4 (0.47) | RBP4CHRM4 | |
| SCHEMBL2636989 | 0.84 | RBP4 (0.52) | RBP4CHRM4 | |
| SCHEMBL17222912 | 0.80 | MAPT (0.51) | RBP4 | |
| SCHEMBL17224430 | 0.80 | RBP4 (0.54) | RBP4 | |
| SCHEMBL2510721 | 0.79 | OPRL1 (0.47) | RBP4 | |
| SCHEMBL2510719 | 0.79 | OPRL1 (0.47) | RBP4 | |
| SCHEMBL17223025 | 0.79 | RBP4 (0.41) | RBP4 | |
| SCHEMBL2636181 | 0.78 | RBP4 (0.49) | RBP4 | |
| SCHEMBL25429337 | 0.78 | SLC9A1 (0.40) | RBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9777010-B2 | Substituted 4-phenylpiperidines, their preparation and use | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-10-03 | — | — | US | disclosed |
| US-20160368925-A1 | SUBSTITUTED 4-PHENYLPIPERIDINES, THEIR PREPARATION AND USE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2016-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160368925-A1 | SUBSTITUTED 4-PHENYLPIPERIDINES, THEIR PREPARATION AND USE | HRH4, HRH3, HRH2 | RBP4 1950/4885CHRM4 82/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.