Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pivalate SCHEMBL28353815 | 0.97 | TSHR (0.47) | TSHRNAPRTTDP1ALDH1A1SLC22A12 | |
| Pyridine SCHEMBL19534751 | 0.86 | ALDH1A1 (0.58) | TSHRNAPRTTDP1ALDH1A1SLC22A12 | |
| Pivalate SCHEMBL28268241 | 0.86 | LMNA (0.39) | TSHRNAPRTTDP1ALDH1A1SLC22A12 | |
| Pivalamide SCHEMBL16446480 | 0.84 | TDP1 (0.45) | TSHRNAPRTTDP1ALDH1A1SLC22A12 | |
| Pyridine SCHEMBL3722502 | 0.84 | TDP1 (0.45) | TSHRNAPRTTDP1ALDH1A1SLC22A12 | |
| Pyridine SCHEMBL19534765 | 0.84 | ALDH1A1 (0.55) | TSHRNAPRTTDP1ALDH1A1SLC22A12 | |
| Pivalate SCHEMBL27686624 | 0.82 | TSHR (0.53) | TSHRALDH1A1KMT2AMEN1CYP1A2 | |
| Pivalate SCHEMBL27675738 | 0.81 | ALDH1A1 (0.36) | TSHRNAPRTALDH1A1SLC22A12KMT2A | |
| Pyridine SCHEMBL11731278 | 0.80 | TSHR (0.41) | TSHRNAPRTTDP1ALDH1A1SLC22A12 | |
| Pyridine SCHEMBL11104571 | 0.79 | TSHR (0.60) | TSHRNAPRTTDP1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1861364-B1 | PREPARATION OF AN ATORVASTATIN INTERMEDIATE USING A PAAL-KNORR CONDENSATION | C P PHARMACEUTICALS INTERNAT C V (US) | 2011-05-11 | — | — | EP | claimed |
| JP-2008533128-A | — | — | 2008-08-21 | — | — | JP | claimed |
| EP-1861364-A1 | PREPARATION OF AN ATORVASTATIN INTERMEDIATE USING A PAAL-KNORR CONDENSATION | Pfizer Science and Technology Ireland Limited (IE) | 2007-12-05 | — | — | EP | claimed |
| WO-2006097909-A1 | PREPARATION OF AN ATORVASTATIN INTERMEDIATE USING A PAAL-KNORR CONDENSATION | PFIZER SCIENCE AND TECHNOLOGY IRELAND LIMITED (IE) | 2006-09-21 | — | — | WO | claimed |
| CN-120519125-A | Preparation method and application of polishing abrasive with cerium cluster coated substrate material | 内蒙古大学 | 2025-08-22 | — | — | CN | disclosed |
| CN-112209917-B | Application of heterocyclic substituted phenylpiperazine or phenylpiperidine derivatives in antidepressant drugs | 上海医药工业研究院 | 2021-09-24 | — | — | CN | disclosed |
| CN-112209917-A | Application of heterocyclic substituted phenyl piperazine (pyridine) derivatives in antidepressant drugs | 上海医药工业研究院 | 2021-01-12 | — | — | CN | disclosed |
| CN-109843892-A | Dislike diazepine ketone derivatives and its purposes in treatment hepatitis B infection | 诺维拉治疗公司 | 2019-06-04 | — | — | CN | disclosed |
| CN-107580595-A | Heterocyclic compounds and their use in the prevention or treatment of bacterial infections | 拜欧蒂姆公司 | 2018-01-12 | — | — | CN | disclosed |
| CN-106573907-A | Novel quinoline derivatives and their use in neurodegenerative diseases | 默克专利有限公司 | 2017-04-19 | — | — | CN | disclosed |
| CN-104663674-A | Fungicidal Mixtures | DU PONT | 2015-06-03 | — | — | CN | disclosed |
| CN-101969781-B | Fungicidal compounds and mixtures | DU PONT | 2015-01-28 | — | — | CN | disclosed |
| EP-1861364-B1 | PREPARATION OF AN ATORVASTATIN INTERMEDIATE USING A PAAL-KNORR CONDENSATION | C P PHARMACEUTICALS INTERNAT C V (US) | 2011-05-11 | — | — | EP | disclosed |
| EP-1861364-A1 | PREPARATION OF AN ATORVASTATIN INTERMEDIATE USING A PAAL-KNORR CONDENSATION | Pfizer Science and Technology Ireland Limited (IE) | 2007-12-05 | — | — | EP | disclosed |
| WO-2006097909-A1 | PREPARATION OF AN ATORVASTATIN INTERMEDIATE USING A PAAL-KNORR CONDENSATION | PFIZER SCIENCE AND TECHNOLOGY IRELAND LIMITED (IE) | 2006-09-21 | — | — | WO | disclosed |