Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 8/20 | 0.73 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 8/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18330542 | 1.00 | HSP90AA1 (0.73) | HSP90AA1XDHSTAT3 | |
| SCHEMBL22360998 | 1.00 | HSP90AA1 (0.73) | HSP90AA1XDHSTAT3 | |
| SCHEMBL27425416 | 0.92 | HSP90AA1 (0.61) | HSP90AA1XDHSTAT3 | |
| SCHEMBL22360997 | 0.79 | HSP90AA1 (0.48) | HSP90AA1XDHSTAT3 | |
| Catalposide SCHEMBL419598 | 0.79 | HSP90AA1 (1.00) | HSP90AA1XDH | |
| SCHEMBL8733913 | 0.75 | HSP90AA1 (0.61) | HSP90AA1 | |
| SCHEMBL382085 | 0.74 | STAT3 (0.44) | HSP90AA1STAT3 | |
| Picroside Ii SCHEMBL24209282 | 0.71 | HSP90AA1 (0.78) | HSP90AA1XDH | |
| Picroside Ii SCHEMBL29367651 | 0.71 | HSP90AA1 (0.78) | HSP90AA1XDH | |
| Picroside Ii SCHEMBL24209283 | 0.71 | HSP90AA1 (0.78) | HSP90AA1XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3310799-A1 | A NOVEL COMPOUND (KS 513) ISOLATED FROM PSEUDOLYSIMACHION ROTUNDUM VAR. SUBINTEGRUM, THE COMPOSITION COMPRISING THE SAME AS AN ACTIVE INGREDIENT FOR PREVENTING OR TREATING ALLERGY DISEASE, INFLAMMATORY DISEASE, ASTHMA OR CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND THE USE THEREOF | Yungjin Pharmaceutical Co., Ltd. (KR) | 2018-04-25 | — | — | EP | claimed |
| US-20180105548-A1 | A novel compound (KS-513) isolated from Pseudolysimachion rotundum var. subintegrum, the composition comprising the same preventing or treating allergic disease, inflammatory disease, asthma or chronic obstructive pulmonary disease and the use thereof | YUNGJIN PHARMACEUTICAL CO., LTD (KR) | 2018-04-19 | — | — | US | claimed |
| WO-2016204493-A1 | A NOVEL COMPOUND (KS 513) ISOLATED FROM PSEUDOLYSIMACHION ROTUNDUM VAR. SUBINTEGRUM, THE COMPOSITION COMPRISING THE SAME AS AN ACTIVE INGREDIENT FOR PREVENTING OR TREATING ALLERGY DISEASE, INFLAMMATORY DISEASE, ASTHMA OR CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND THE USE THEREOF | YUNGJIN PHARMACEUTICAL., LTD. (KR) | 2016-12-22 | — | — | WO | claimed |
| EP-3310799-B1 | A NOVEL COMPOUND (KS 513) ISOLATED FROM PSEUDOLYSIMACHION ROTUNDUM VAR. SUBINTEGRUM AND THE COMPOSITION COMPRISING THE SAME AS AN ACTIVE INGREDIENT FOR PREVENTING OR TREATING ALLERGY DISEASE, INFLAMMATORY DISEASE, ASTHMA OR CHRONIC OBSTRUCTIVE PULMONARY DISEASE | YUNGJIN PHARMACEUTICAL CO LTD (KR) | 2020-08-26 | — | — | EP | disclosed |
| EP-3310799-A1 | A NOVEL COMPOUND (KS 513) ISOLATED FROM PSEUDOLYSIMACHION ROTUNDUM VAR. SUBINTEGRUM, THE COMPOSITION COMPRISING THE SAME AS AN ACTIVE INGREDIENT FOR PREVENTING OR TREATING ALLERGY DISEASE, INFLAMMATORY DISEASE, ASTHMA OR CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND THE USE THEREOF | Yungjin Pharmaceutical Co., Ltd. (KR) | 2018-04-25 | — | — | EP | disclosed |
| EP-3310799-A1 | A NOVEL COMPOUND (KS 513) ISOLATED FROM PSEUDOLYSIMACHION ROTUNDUM VAR. SUBINTEGRUM, THE COMPOSITION COMPRISING THE SAME AS AN ACTIVE INGREDIENT FOR PREVENTING OR TREATING ALLERGY DISEASE, INFLAMMATORY DISEASE, ASTHMA OR CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND THE USE THEREOF | Yungjin Pharmaceutical Co., Ltd. (KR) | 2018-04-25 | — | — | EP | disclosed |
| CN-106715452-A | A novel compound (ks 513) isolated from pseudolysimachion rotundum var. subintegrum, the composition comprising the same as an active ingredient for preventing or treating allergy disease, inflammatory disease, asthma or chronic obstructive pulmonary disease and the use thereof | 永进药品株式会社 | 2017-05-24 | — | — | CN | disclosed |
| WO-2016204493-A1 | A NOVEL COMPOUND (KS 513) ISOLATED FROM PSEUDOLYSIMACHION ROTUNDUM VAR. SUBINTEGRUM, THE COMPOSITION COMPRISING THE SAME AS AN ACTIVE INGREDIENT FOR PREVENTING OR TREATING ALLERGY DISEASE, INFLAMMATORY DISEASE, ASTHMA OR CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND THE USE THEREOF | YUNGJIN PHARMACEUTICAL., LTD. (KR) | 2016-12-22 | — | — | WO | disclosed |
| WO-2016204493-A1 | A NOVEL COMPOUND (KS 513) ISOLATED FROM PSEUDOLYSIMACHION ROTUNDUM VAR. SUBINTEGRUM, THE COMPOSITION COMPRISING THE SAME AS AN ACTIVE INGREDIENT FOR PREVENTING OR TREATING ALLERGY DISEASE, INFLAMMATORY DISEASE, ASTHMA OR CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND THE USE THEREOF | YUNGJIN PHARMACEUTICAL., LTD. (KR) | 2016-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180105548-A1 | A novel compound (KS-513) isolated from Pseudolysimachion rotundum var. subintegrum, the composition comprising the same preventing or treating allergic disease, inflammatory disease, asthma or chronic obstructive pulmonary disease and the use thereof | KLK5, LTA4H, KCNK5 | HSP90AA1 4182/4885XDH 1361/4885STAT3 2079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.