Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | SPR | P35270 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ASPH | Q12797 | 1/20 | 0.37 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18320808 | 0.88 | POLB (0.40) | POLBKDM4EL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL18320768 | 0.85 | KDM4E (0.40) | POLBKDM4EL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL18328058 | 0.82 | KDM4E (0.39) | POLBKDM4EL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL14206628 | 0.82 | POLB (0.43) | POLBKDM4EL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL18362975 | 0.81 | NOS3 (0.51) | POLBKDM4EL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL31266744 | 0.81 | POLB (0.49) | POLBKDM4EL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL4782685 | 0.81 | POLB (0.49) | POLBKDM4EL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL14206660 | 0.81 | POLB (0.49) | POLBKDM4EL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL12072208 | 0.77 | RXFP1 (0.48) | POLBKDM4EL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL31396339 | 0.76 | KDM4E (0.44) | POLBKDM4EL3MBTL1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016202898-A1 | GLUCOSE TRANSPORT INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-12-22 | — | — | WO | disclosed |