Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 8/20 | 0.57 |
| ▸ | HTR1A | P08908 | 6/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 6/20 | 0.57 |
| ▸ | ADRA2B | P18089 | 6/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 6/20 | 0.57 |
| ▸ | HTR1D | P28221 | 6/20 | 0.57 |
| ▸ | HTR2A | P28223 | 6/20 | 0.57 |
| ▸ | HTR2C | P28335 | 6/20 | 0.57 |
| ▸ | HTR1E | P28566 | 6/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.57 |
| ▸ | HRH1 | P35367 | 6/20 | 0.57 |
| ▸ | DRD3 | P35462 | 6/20 | 0.57 |
| ▸ | HTR2B | P41595 | 6/20 | 0.57 |
| ▸ | HTR6 | P50406 | 6/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.57 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6536337 | 0.89 | ALDH1A1 (0.47) | OPRK1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL18589310 | 0.84 | CYP2D6 (0.56) | OPRK1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL18929757 | 0.84 | CYP1A2 (0.53) | HTR1AHTR2AKDM4ECYP1A2CYP2C19 | |
| SCHEMBL18085058 | 0.80 | HTR1A (0.76) | OPRK1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL24152350 | 0.80 | CYP2D6 (0.51) | OPRK1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL8721975 | 0.77 | CDYL (0.61) | HTR1AHTR1DHTR2AHTR6KDM4E | |
| SCHEMBL5516425 | 0.77 | CYP1A2 (0.48) | ALDH1A1KDM4EHPGDMEN1POLB | |
| SCHEMBL29891134 | 0.77 | CYP1A2 (0.48) | ALDH1A1KDM4EHPGDMEN1POLB | |
| SCHEMBL11304680 | 0.76 | HTR1A (0.59) | OPRK1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL20565292 | 0.76 | TAAR1 (0.55) | OPRK1HTR1AADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016202894-A1 | METHOD OF CONVERTING ALCOHOL TO HALIDE | UNIVERSITAET DES SAARLANDES (DE) | 2016-12-22 | — | — | WO | disclosed |