SCHEMBL18320702

SCHEMBL18320702

CCN(C)/C=N\c1cc(Cl)c(Oc2ccccc2Cl)cc1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 8/20 0.41
SLC6A3 Q01959 8/20 0.41
SLC6A4 P31645 7/20 0.41
AR P10275 1/20 0.35
HPGD P15428 3/20 0.33
L3MBTL1 Q9Y468 3/20 0.33
NPC1 O15118 2/20 0.33
MAPT P10636 2/20 0.33
RAB9A P51151 2/20 0.33
CYP3A4 P08684 2/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CXCL8 P10145 1/20 0.32
ADRA2A P08913 1/20 0.32
LPAR1 Q92633 1/20 0.31
LPAR5 Q9H1C0 1/20 0.31
CAMK2A Q9UQM7 1/20 0.31
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18320704 1.00 SLC6A2 (0.41) SLC6A2SLC6A3SLC6A4ARHPGD
SCHEMBL21779547 0.93 SLC6A2 (0.41) SLC6A2SLC6A3SLC6A4ARHPGD
SCHEMBL29441506 0.90 SLC6A2 (0.37) SLC6A2SLC6A3SLC6A4ARHPGD
SCHEMBL21782711 0.90 LMNA (0.34) SLC6A2SLC6A3SLC6A4ARHPGD
SCHEMBL18320495 0.90 LMNA (0.34) SLC6A2SLC6A3SLC6A4ARHPGD
SCHEMBL18320660 0.90 SLC6A2 (0.33) SLC6A2SLC6A3SLC6A4ARCYP3A4
SCHEMBL18320661 0.90 SLC6A2 (0.33) SLC6A2SLC6A3SLC6A4ARCYP3A4
SCHEMBL18331587 0.90 SLC6A2 (0.37) SLC6A2SLC6A3SLC6A4ARHPGD
SCHEMBL18320497 0.90 LMNA (0.34) SLC6A2SLC6A3SLC6A4ARHPGD
SCHEMBL29352071 0.90 LMNA (0.34) SLC6A2SLC6A3SLC6A4ARHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3307706-B1 HALOGEN-SUBSTITUTED PHENOXYPHENYLAMIDINES AND THE USE THEREOF AS FUNGICIDES BAYER CROPSCIENCE AG (DE) 2019-07-24 EP claimed
US-10252977-B2 Halogen-substituted phenoxyphenylamidines and the use thereof as fungicides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-04-09 US claimed
US-20180186724-A1 Halogen-substituted phenoxyphenylamidines and the use thereof as fungicides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-07-05 US claimed
EP-3307706-A1 HALOGEN-SUBSTITUTED PHENOXYPHENYLAMIDINES AND THE USE THEREOF AS FUNGICIDES Bayer CropScience AG (DE) 2018-04-18 EP claimed
WO-2016202688-A1 HALOGEN-SUBSTITUTED PHENOXYPHENYLAMIDINES AND THE USE THEREOF AS FUNGICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-12-22 WO claimed
EP-3307706-B1 HALOGEN-SUBSTITUTED PHENOXYPHENYLAMIDINES AND THE USE THEREOF AS FUNGICIDES BAYER CROPSCIENCE AG (DE) 2019-07-24 EP disclosed
US-10252977-B2 Halogen-substituted phenoxyphenylamidines and the use thereof as fungicides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-04-09 US disclosed
US-20180186724-A1 Halogen-substituted phenoxyphenylamidines and the use thereof as fungicides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-07-05 US disclosed
EP-3307706-A1 HALOGEN-SUBSTITUTED PHENOXYPHENYLAMIDINES AND THE USE THEREOF AS FUNGICIDES Bayer CropScience AG (DE) 2018-04-18 EP disclosed
WO-2016202688-A1 HALOGEN-SUBSTITUTED PHENOXYPHENYLAMIDINES AND THE USE THEREOF AS FUNGICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-12-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10252977-B2 Halogen-substituted phenoxyphenylamidines and the use thereof as fungicides PFAS, DDT, PAH SLC6A2 1839/4885SLC6A3 1298/4885SLC6A4 1365/4885
US-20180186724-A1 Halogen-substituted phenoxyphenylamidines and the use thereof as fungicides PFAS, DDT, PAH SLC6A2 1839/4885SLC6A3 1298/4885SLC6A4 1365/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.