SCHEMBL1832088

SCHEMBL1832088

CC(O)C(O)C(O)C(O)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
PDE4A P27815 1/20 0.50
TP53 P04637 1/20 0.47
CYP2C9 P11712 1/20 0.44
ALDH1A1 P00352 1/20 0.41
SLC7A5 Q01650 1/20 0.33
NFKB1 P19838 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL265598 1.00 TSHR (0.50) TSHRPDE4ATP53CYP2C9ALDH1A1
SCHEMBL17887907 1.00 TSHR (0.50) TSHRPDE4ATP53CYP2C9ALDH1A1
SCHEMBL29709585 1.00 TSHR (0.50) TSHRPDE4ATP53CYP2C9ALDH1A1
SCHEMBL11059297 1.00 TSHR (0.50) TSHRPDE4ATP53CYP2C9ALDH1A1
SCHEMBL12904430 1.00 TSHR (0.50) TSHRPDE4ATP53CYP2C9ALDH1A1
SCHEMBL19127751 1.00 TSHR (0.50) TSHRPDE4ATP53CYP2C9ALDH1A1
SCHEMBL7148974 1.00 TSHR (0.50) TSHRPDE4ATP53CYP2C9ALDH1A1
SCHEMBL28773455 0.97 PDE4A (0.48) TSHRPDE4ATP53CYP2C9ALDH1A1
SCHEMBL4049818 0.92 PDE4A (0.44) TSHRPDE4ATP53CYP2C9ALDH1A1
SCHEMBL15841482 0.91 TSHR (0.53) TSHRPDE4ATP53CYP2C9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118109820-A Copper etching solution composition for reducing copper corrosion and etching crystallization after stripping and washing 西陇科学股份有限公司 2024-05-31 CN claimed
CN-114945560-A GPR119 agonists 卡尔优普公司 2022-08-26 CN claimed
CN-113717381-B Rhamnosyl linear and dendritic-star polymer, preparation method and application 中国海洋大学 2022-06-21 CN claimed
CN-113717381-A Rhamnosyl linear and dendritic-star polymer, preparation method and application 中国海洋大学 2021-11-30 CN claimed
CN-108699028-A It is substituted 4- phenylpyridine compounds as non-systemic TGR5 agonists 阿德利克斯公司 2018-10-23 CN claimed
US-20250223392-A1 HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF ALCON INC (CH) 2025-07-10 US disclosed
US-12286501-B2 Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof ALCON INC. (CH) 2025-04-29 US disclosed
US-20250127925-A1 DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO HERCULES CAPITAL, INC. 2025-04-24 US disclosed
US-20250059330-A1 SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2025-02-20 US disclosed
EP-4481478-A2 SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2024-12-25 EP disclosed
US-12162987-B2 Silicone hydrogel contact lenses ALCON INC. (CH) 2024-12-10 US disclosed
EP-4235274-B1 SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2024-10-09 EP disclosed
WO-2016131672-A1 2,3,4,5-TETRAHYDROXY-HEXANEDIOIC ACID ESTERS FROM DI-LACTONES OF 2,3,4,5-TETRAHYDROXY-HEXANEDIOIC ACID BASF SE (DE) 2016-08-25 WO disclosed
US-20160235863-A1 DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO HERCULES CAPITAL, INC. 2016-08-18 US disclosed
US-20150307444-A1 CLASS- AND ISOFORM-SPECIFIC HDAC INHIBITORS AND USES THEREOF PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2015-10-29 US disclosed
US-8716344-B2 Class- and isoform-specific HDAC inhibitors and uses thereof PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2014-05-06 US disclosed
US-20120046533-A1 COMBINED SENSOR AND INFUSION SETS MEDTRONIC MINIMED, INC. (US) 2012-02-23 US disclosed
US-20110160036-A1 VALVE METAL OXIDE FORMULATION H.C. STARCK GMBH (DE) 2011-06-30 US disclosed
EP-2318325-A2 VALVE METAL OXIDE FORMULATION H.C. Starck GmbH (DE) 2011-05-11 EP disclosed
WO-2010026016-A2 VALVE METAL OXIDE FORMULATION H.C. STARCK GMBH (DE) 2010-03-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250127925-A1 DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO CSGALNACT1, CHI3L2, LNPEP TSHR 4331/4885PDE4A 4587/4885TP53 1908/4885
US-20150307444-A1 CLASS- AND ISOFORM-SPECIFIC HDAC INHIBITORS AND USES THEREOF HDAC1, HDAC5, HDAC6 TSHR 3987/4885PDE4A 2225/4885TP53 1611/4885
US-20160235863-A1 DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO CSGALNACT1, CHI3L2, LNPEP TSHR 4331/4885PDE4A 4587/4885TP53 1908/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.