CHI3L2

Chitinase-3-like protein 2 · Q15782 · CHI3L2 on Sugi Atlas →

1,423 patent compounds predicted against CHI3L2, 976 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL26210308	1.00	4/20
SCHEMBL26210194	0.87	4/20
Trifluoroacetic Acid (SCHEMBL25385660)	0.87	4/20
Trifluoroacetic Acid (SCHEMBL25385221)	0.85	4/20
SCHEMBL26210129	0.82	4/20
SCHEMBL26210110	0.81	4/20
SCHEMBL26210095	0.79	4/20
SCHEMBL26210098	0.78	4/20
SCHEMBL26210102	0.77	4/20
SCHEMBL26210138	0.77	4/20
SCHEMBL26210232	0.76	4/20
SCHEMBL26210462	0.76	4/20
SCHEMBL26210512	0.76	4/20
SCHEMBL26210135	0.75	4/20
SCHEMBL26210418	0.75	4/20
SCHEMBL26210461	0.75	4/20
Hydrochloric Acid (SCHEMBL25384955)	0.75	4/20
Hydrochloric Acid (SCHEMBL25384702)	0.75	4/20
SCHEMBL26210417	0.75	4/20
SCHEMBL26210419	0.75	4/20

Clinical trials — most relevant to CHI3L2 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Allogeneic Adipose Tissue-derived Mesenchymal Stem Cells in Ischemic Stroke	PHASE2	UNKNOWN
Exploration Of Key Targets And Biomarkers Involved In An Allergic Response In Subjects With Allergic Rhinitis (Hay Fever)	PHASE1	COMPLETED
GSNOR Phenotyping/GSNO Challenge in Severe Asthma	EARLY_PHASE1	COMPLETED
The Relationship Between Single Nucleotide Polymorphisms of Chitinase 3-like 1 Gene,YKL-40 Serum Levels and Adult Asthma	nan	UNKNOWN
The Role of Peripheral and Tissue Chitinase 3-like 1 Protein Levels as a Bio-marker in IBD	nan	COMPLETED
Tear Proteins, Conjunctival Cells and Imaging Eyes in Rheumatoid Arthritis and Systemic Lupus Erythematosus Patients	nan	COMPLETED
National Psoriasis Foundation - Dendritic Cell-Specific Transmembrane Protein (DC-Stamp) Biomarker Study	nan	COMPLETED
The Genetics of Chiari Type I Malformation	nan	COMPLETED
Chitinases and Transforming Growth Factor Beta (TGFB) in Human Asthma	nan	COMPLETED
The Role of Quantitative CT and Radiomic Biomarkers for Precision Medicine in Pulmonary Fibrosis	nan	RECRUITING
Transcriptional and Immune Parameters of Response to Belimumab	nan	COMPLETED
Studying Genes in Samples From Younger Patients With Ovarian or Testicular Sex Cord Stromal Tumors	nan	COMPLETED
Multi-Vendor Multi-Site Novel Accelerated MRI Relaxometry	nan	RECRUITING
Comparison of Uncomplicated Candidemia Therapy Duration in Children	nan	RECRUITING
Transforming Research and Clinical Knowledge in Traumatic Brain Injury	nan	COMPLETED
Evaluation of the Association of Polymorphisms in the Innate Immune System With the Risk for Cryptococcus Neoformans Infection in Patients Not Infected With HIV and Complications Associated With Cryptococcus Neoformans Infection	nan	COMPLETED
Belimumab in SLE Synovial Inflammation and Lymph Nodes	nan	UNKNOWN
Expression of Inflammatory Proteins in Pancreatic Cancer	nan	UNKNOWN
Glycoprotein and Glycan in Tissue and Blood Samples of Patients With Stage IB-IVA Cervical Cancer Undergoing Surgery to Remove Pelvic and Abdominal Lymph Nodes	nan	COMPLETED
Development and Validation of a Nomogram for Predicting Surgery in Newly-diagnosed Crohn's Disease: a Retrospective Cohort Study	nan	COMPLETED
Biomarker for Mannosidosis Disease (BioMannosidosis)	nan	WITHDRAWN
Evaluation of TNF-α, IL-17A, and YKL-40 in GCF and Serum of Psoriasis Patients and Healthy Controls	nan	ACTIVE_NOT_RECRUITING
Evaluation of the Association of Polymorphisms in the Innate Immune System With the Risk for Blastomycosis Dermatitidis Infection in Patients Not Infected With HIV and Complications Associated With Blastomycosis Dermatitidis Infection	nan	COMPLETED
Salivary Biomarkers in Pediatric Traumatic Brain Injury	nan	COMPLETED
miRNAs Profiling in Parkinson's Disease	nan	COMPLETED
Biomarker Levels as A Predictor of Concussion Severity OUTcomes (BlacOut)	nan	COMPLETED
NCF Gene & TNFSF4 in SLE Patients	nan	UNKNOWN
Depression, Obesity and Inflammatory Markers	nan	COMPLETED
Inflammatory Mediators as Potential Non-Invasive Biomarkers in Subjects With Eosinophilic Esophagitis	nan	ACTIVE_NOT_RECRUITING
Biomarker for Mucolipidosis Disorder Type I, II, III, IV (BioML)	nan	WITHDRAWN

Related proteins — ESM-2 sequence neighbours (a CHI3L2 binder may also engage these)

Protein	Name	Similarity
O35744	—	0.999	O35744 →
Q91Z98	—	0.994	Q91Z98 →
Q61362	—	0.994	Q61362 →
Q9WTV1	—	0.994	Q9WTV1 →
Q7YS85	—	0.991	Q7YS85 →
P30922	—	0.990	P30922 →
Q5RBP6	—	0.990	Q5RBP6 →
CHI3L1	Chitinase-3-like protein 1	0.989	landscape →
Q29411	—	0.986	Q29411 →
Q8SPQ0	—	0.985	Q8SPQ0 →
CHIT1	Chitotriosidase-1	0.983	landscape →
Q6TMG6	—	0.983	Q6TMG6 →
Q9D7Q1	—	0.982	Q9D7Q1 →
Q2PQM7	—	0.980	Q2PQM7 →
Q9V3D4	—	0.977	Q9V3D4 →
Q8T0R7	—	0.977	Q8T0R7 →
Q9GV28	—	0.976	Q9GV28 →
Q2PQM6	—	0.975	Q2PQM6 →
Q8MM24	—	0.974	Q8MM24 →
Q2PQN0	—	0.973	Q2PQN0 →
P29030	—	0.973	P29030 →
Q8MX40	—	0.973	Q8MX40 →
O82772	—	0.973	O82772 →
Q9W303	—	0.972	Q9W303 →
Q95M17	—	0.972	Q95M17 →
B3H5Q1	—	0.972	B3H5Q1 →
Q8MX41	—	0.971	Q8MX41 →
A0A1S4F0I0	—	0.971	A0A1S4F0I0 →
Q8MX31	—	0.971	Q8MX31 →
Q8MX32	—	0.971	Q8MX32 →