Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KYNU | Q16719 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 2/20 | 0.55 |
| ▸ | CTSK | P43235 | 7/20 | 0.54 |
| ▸ | CTSL | P07711 | 6/20 | 0.51 |
| ▸ | CTSS | P25774 | 4/20 | 0.51 |
| ▸ | CTSB | P07858 | 2/20 | 0.51 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1837491 | 1.00 | KYNU (0.57) | KYNUALDH1A1ALOX15CASP1CTSK | |
| SCHEMBL21837386 | 0.91 | KYNU (0.58) | KYNUALDH1A1ALOX15CASP1CTSK | |
| SCHEMBL21837385 | 0.91 | KYNU (0.58) | KYNUALDH1A1ALOX15CASP1CTSK | |
| SCHEMBL28162782 | 0.90 | KYNU (0.60) | KYNUALDH1A1ALOX15CASP1CTSK | |
| SCHEMBL5191992 | 0.90 | KYNU (0.60) | KYNUALDH1A1ALOX15CASP1CTSK | |
| SCHEMBL16351361 | 0.89 | KYNU (0.62) | KYNUALDH1A1ALOX15CTSKCTSL | |
| SCHEMBL31604948 | 0.89 | KYNU (0.56) | KYNUALDH1A1ALOX15CASP1CTSK | |
| SCHEMBL2913109 | 0.89 | KYNU (0.56) | KYNUALDH1A1ALOX15CASP1CTSK | |
| SCHEMBL527104 | 0.88 | CTSK (0.64) | KYNUALDH1A1ALOX15CTSKCTSL | |
| SCHEMBL4387860 | 0.88 | CTSK (0.64) | KYNUALDH1A1ALOX15CTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321287-A1 | 4,5-DIHYDRO-OXAZOL-2-YL DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2011-05-18 | — | — | EP | disclosed |
| WO-2010010014-A1 | 4,5-DIHYDRO-OXAZOL-2-YL DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2010-01-28 | — | — | WO | disclosed |