SCHEMBL18327173

SCHEMBL18327173

O=C(Nc1cccc(NC(=O)c2ccccc2O)c1)c1ccccc1O

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.79
KMT2A Q03164 5/20 0.79
LMNA P02545 4/20 0.79
KDM4E B2RXH2 3/20 0.79
TP53 P04637 3/20 0.79
HTT P42858 3/20 0.79
HSD17B10 Q99714 2/20 0.79
HPGD P15428 2/20 0.79
P2RX1 P51575 4/20 0.78
FADS1 O60427 1/20 0.78
TERT O14746 1/20 0.77
NPC1 O15118 3/20 0.70
RAB9A P51151 2/20 0.70
POLB P06746 1/20 0.69
ALOX15 P16050 3/20 0.66
NFKB1 P19838 1/20 0.64
NFKB2 Q00653 1/20 0.64
RELA Q04206 1/20 0.64
SMN1; SMN2 Q16637 1/20 0.64
ALDH1A1 P00352 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4372468 0.91 P2RX1 (0.71) MEN1KMT2ALMNAKDM4ETP53
Salicylanilide SCHEMBL20165864 0.88 MEN1 (1.00) MEN1KMT2ALMNAKDM4ETP53
Salicylanilide SCHEMBL14051034 0.88 MEN1 (1.00) MEN1KMT2ALMNAKDM4ETP53
Salicylanilide SCHEMBL152221 0.88 MEN1 (1.00) MEN1KMT2ALMNAKDM4ETP53
Salicylanilide SCHEMBL28262329 0.88 MEN1 (1.00) MEN1KMT2ALMNAKDM4ETP53
SCHEMBL2701738 0.88 FADS1 (1.00) MEN1KMT2ALMNAKDM4ETP53
SCHEMBL16941525 0.88 MEN1 (0.72) MEN1KMT2ALMNAKDM4ETP53
SCHEMBL2700843 0.88 P2RX1 (1.00) MEN1KMT2ALMNAKDM4ETP53
SCHEMBL2699846 0.88 P2RX1 (0.68) MEN1KMT2ALMNAKDM4ETP53
SCHEMBL17005794 0.87 TERT (1.00) MEN1KMT2ALMNAKDM4ETP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9896465-B2 Phosphonium compound, preparation method thereof, epoxy resin composition including the same, and semiconductor device prepared by using the same SAMSUNG SDI CO., LTD. (KR) 2018-02-20 US disclosed
US-9896465-B2 Phosphonium compound, preparation method thereof, epoxy resin composition including the same, and semiconductor device prepared by using the same SAMSUNG SDI CO., LTD. (KR) 2018-02-20 US disclosed
US-20160368937-A1 PHOSPHONIUM COMPOUND, PREPARATION METHOD THEREOF, EPOXY RESIN COMPOSITION INCLUDING THE SAME, AND SEMICONDUCTOR DEVICE PREPARED BY USING THE SAME SAMSUNG SDI CO., LTD. (KP) 2016-12-22 US disclosed
US-20160368937-A1 PHOSPHONIUM COMPOUND, PREPARATION METHOD THEREOF, EPOXY RESIN COMPOSITION INCLUDING THE SAME, AND SEMICONDUCTOR DEVICE PREPARED BY USING THE SAME SAMSUNG SDI CO., LTD. (KP) 2016-12-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160368937-A1 PHOSPHONIUM COMPOUND, PREPARATION METHOD THEREOF, EPOXY RESIN COMPOSITION INCLUDING THE SAME, AND SEMICONDUCTOR DEVICE PREPARED BY USING THE SAME PHOSPHO1, PPA1, ASH2L MEN1 1123/4885KMT2A 1635/4885LMNA 4549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.