Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4594325 | 0.87 | HTT (0.44) | PTPN11HTTPTPN2PTPN1THRB | |
| SCHEMBL12731853 | 0.87 | HTT (0.44) | PTPN11HTTPTPN2PTPN1THRB | |
| SCHEMBL12731850 | 0.87 | HTT (0.44) | PTPN11HTTPTPN2PTPN1THRB | |
| SCHEMBL815840 | 0.87 | HTT (0.44) | PTPN11HTTPTPN2PTPN1THRB | |
| SCHEMBL19757188 | 0.87 | HTT (0.40) | PTPN11HTTTHRBCYP3A4ALDH1A1 | |
| SCHEMBL8913193 | 0.86 | HTT (0.43) | PTPN11HTTPTPN2PTPN1THRB | |
| SCHEMBL8913978 | 0.86 | HTT (0.43) | PTPN11HTTPTPN2PTPN1THRB | |
| SCHEMBL18328868 | 0.86 | THRB (0.45) | PTPN11HTTPTPN2PTPN1THRB | |
| SCHEMBL8913449 | 0.86 | HTT (0.43) | PTPN11HTTPTPN2PTPN1THRB | |
| SCHEMBL8912528 | 0.86 | HTT (0.43) | PTPN11HTTPTPN2PTPN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160370626-A1 | LIQUID CRYSTAL DISPLAY DEVICE | DIC CORPORATION (JP) | 2016-12-22 | — | — | US | disclosed |