Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.39 |
| ▸ | RELA | Q04206 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | ACR | P10323 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19497942 | 0.94 | ALDH1A1 (0.40) | HTTNPC1LMNANFKB1NFKB2 | |
| SCHEMBL18200278 | 0.91 | MAPT (0.44) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL19352701 | 0.91 | HTT (0.41) | HTTNPC1LMNANFKB1NFKB2 | |
| SCHEMBL19497864 | 0.90 | MAPT (0.45) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL19497859 | 0.88 | MAPT (0.45) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL18328867 | 0.87 | PTPN11 (0.46) | HTTNPC1LMNANFKB1NFKB2 | |
| SCHEMBL15478710 | 0.87 | HTT (0.42) | HTTNPC1LMNANFKB1NFKB2 | |
| SCHEMBL19497943 | 0.85 | ALDH1A1 (0.40) | HTTNPC1LMNANFKB1NFKB2 | |
| SCHEMBL19792473 | 0.85 | HTT (0.39) | HTTNPC1LMNANFKB1NFKB2 | |
| SCHEMBL19844183 | 0.85 | THRB (0.48) | HTTTHRBCYP3A4ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180037817-A1 | POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY | DIC CORPORATION (JP) | 2018-02-08 | — | — | US | disclosed |
| US-20180037817-A1 | POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY | DIC CORPORATION (JP) | 2018-02-08 | — | — | US | disclosed |
| US-20180022716-A1 | POLYMERIZABLE COMPOUND AND OPTICAL ISOMER | DIC CORPORATION (JP) | 2018-01-25 | — | — | US | disclosed |
| US-20180022716-A1 | POLYMERIZABLE COMPOUND AND OPTICAL ISOMER | DIC CORPORATION (JP) | 2018-01-25 | — | — | US | disclosed |
| US-20170369783-A1 | POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC OBJECT | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) | 2017-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180022716-A1 | POLYMERIZABLE COMPOUND AND OPTICAL ISOMER | SMC4, MAP1LC3C, ZW10 | HTT 1451/4885NPC1 4194/4885LMNA 637/4885 |
| US-20170369783-A1 | POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC OBJECT | VIM, SMCHD1, SMC4 | HTT 410/4885NPC1 3002/4885LMNA 1275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.