Mandelic Acid

Mandelic Acid

SCHEMBL1832891

CC(N)O.O=C(O)[C@H](O)c1ccccc1

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.78
MAPK1 P28482 1/20 0.78
ADRA2A P08913 1/20 0.54
ADRA2C P18825 1/20 0.54
HIF1A Q16665 1/20 0.54
KDM4E B2RXH2 1/20 0.54
ALDH1A1 P00352 1/20 0.52
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52
HPGD P15428 1/20 0.52
SRC P12931 2/20 0.48
CYP2D6 P10635 1/20 0.48
ALOX5 P09917 1/20 0.46
KEAP1 Q14145 1/20 0.45
NFE2L2 Q16236 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mandelic Acid SCHEMBL1832893 1.00 LMNA (0.78) LMNAMAPK1ADRA2AADRA2CHIF1A
Mandelic Acid SCHEMBL28826203 0.92 LMNA (0.72) LMNAMAPK1ADRA2AADRA2CHIF1A
Mandelic Acid SCHEMBL28053312 0.92 LMNA (0.72) LMNAMAPK1ADRA2AADRA2CHIF1A
Mandelic Acid SCHEMBL1275427 0.91 LMNA (0.86) LMNAMAPK1ADRA2AADRA2CHIF1A
Mandelic Acid SCHEMBL8630179 0.89 LMNA (0.82) LMNAMAPK1ADRA2AADRA2CKDM4E
Mandelic Acid SCHEMBL7279536 0.89 LMNA (0.90) LMNAMAPK1KDM4EALDH1A1CES2
Mandelic Acid SCHEMBL6056301 0.89 LMNA (0.90) LMNAMAPK1ADRA2AADRA2CKDM4E
Mandelic Acid SCHEMBL8876737 0.89 LMNA (0.90) LMNAMAPK1ADRA2AADRA2CKDM4E
Mandelic Acid SCHEMBL29777368 0.89 LMNA (1.00) LMNAMAPK1KDM4EALDH1A1CES2
Mandelic Acid SCHEMBL5313046 0.89 LMNA (1.00) LMNAMAPK1KDM4EALDH1A1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9328220-B2 Liquids INNOVIA FILMS LIMITED (GB) 2016-05-03 US disclosed
US-8992798-B2 Liquids INNOVIA FILMS LIMITED (GB) 2015-03-31 US disclosed
US-8784686-B2 Liquids INNOVIA FILMS LIMITED (GB) 2014-07-22 US disclosed
US-20140187684-A1 LIQUIDS INNOVIA FILMS LIMITED (GB) 2014-07-03 US disclosed
US-20110257433-A1 LIQUIDS THE UNIVERSITY OF YORK (GB) 2011-10-20 US disclosed
EP-2322497-A1 Ionic liquids comprising nitrogen containing cations Innovia Films Limited (GB) 2011-05-18 EP disclosed
US-20070185330-A1 Liquids THE UNIVERSITY OF YORK (GB) 2007-08-09 US disclosed
US-4234599-A Treatment of skin keratoses with α-hydroxy acids and related compounds SCOTT EUGENE J VAN 1980-11-18 US disclosed