Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.72 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mandelic Acid SCHEMBL28826203 | 1.00 | LMNA (0.72) | LMNAMAPK1HIF1AKDM4EADRA2A | |
| Mandelic Acid SCHEMBL1832893 | 0.92 | LMNA (0.78) | LMNAMAPK1HIF1AKDM4EADRA2A | |
| Mandelic Acid SCHEMBL1832891 | 0.92 | LMNA (0.78) | LMNAMAPK1HIF1AKDM4EADRA2A | |
| Mandelic Acid SCHEMBL1275427 | 0.87 | LMNA (0.86) | LMNAMAPK1HIF1AKDM4EADRA2A | |
| Mandelic Acid SCHEMBL8630179 | 0.85 | LMNA (0.82) | LMNAMAPK1KDM4EADRA2AADRA2C | |
| Mandelic Acid SCHEMBL7279536 | 0.85 | LMNA (0.90) | LMNAMAPK1KDM4EHPGDALDH1A1 | |
| Mandelic Acid SCHEMBL8876737 | 0.85 | LMNA (0.90) | LMNAMAPK1KDM4EADRA2AADRA2C | |
| Mandelic Acid SCHEMBL6056301 | 0.85 | LMNA (0.90) | LMNAMAPK1KDM4EADRA2AADRA2C | |
| Bicarbonate SCHEMBL27964415 | 0.85 | LMNA (0.54) | LMNAMAPK1HIF1AKDM4EADRA2A | |
| Mandelic Acid SCHEMBL29777368 | 0.85 | LMNA (1.00) | LMNAMAPK1KDM4EHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105294427-A | Resolving synthetic method for paramethoxymandelic acid | SHANGHAI YURLIC CHEMICAL S&T CO LTD | 2016-02-03 | — | — | CN | disclosed |