SCHEMBL1832989

SCHEMBL1832989

NCCCCC(C(=O)O)N1C(=O)C=CC1=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.44
CPB2 Q96IY4 9/20 0.43
RNPEP Q9H4A4 1/20 0.43
CPB1 P15086 2/20 0.41
DNMT1 P26358 1/20 0.40
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
TP53 P04637 1/20 0.37
GLA P06280 1/20 0.37
POLB P06746 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
HPGD P15428 1/20 0.37
ALOX12 P18054 1/20 0.37
NFKB1 P19838 1/20 0.37
APEX1 P27695 1/20 0.37
MAPK1 P28482 1/20 0.37
HSD17B10 Q99714 1/20 0.37
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31509482 0.95 CPB2 (0.43) GSRCPB2RNPEPCPB1DNMT1
Trifluoroacetic Acid SCHEMBL31509512 0.86 HRH4 (0.37) GSRCPB2CPB1DNMT1KDM4E
SCHEMBL30469023 0.85 CPB2 (0.39) GSRCPB2RNPEPCPB1ALDH1A1
SCHEMBL6939609 0.83 GPR84 (0.43) DNMT1KDM4EALDH1A1TP53GLA
SCHEMBL30634818 0.81 GPR84 (0.46) DNMT1
SCHEMBL6940135 0.81 GPR84 (0.46) DNMT1
SCHEMBL6934782 0.81 GPR84 (0.46) DNMT1
SCHEMBL1574549 0.81 GPR84 (0.46) DNMT1
SCHEMBL43883 0.81 GPR84 (0.46) DNMT1
SCHEMBL29505890 0.81 KDM4E (0.49) DNMT1KDM4EALDH1A1TP53GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1534324-B1 TUMOR SPECIFIC OLIGOSACCHARIDE EPITOPES AND USE THEREOF GLYKOS FINLAND OY (FI) 2019-01-16 EP disclosed
US-20180055928-A1 Tumor specific oligosaccharide epitopes and use thereof GLYKOS FINLAND OY (FI) 2018-03-01 US disclosed
US-20140234318-A1 TUMOR SPECIFIC OLIGOSACCHARIDE EPITOPES AND USE THEREOF GLYKOS FINLAND OY (FI) 2014-08-21 US disclosed
US-8697061-B2 Tumor specific oligosaccharide epitopes and use thereof GLYKOS FINLAND OY (FI) 2014-04-15 US disclosed
EP-2322209-A2 Tumor specific oligosaccharide epitopes and use thereof Glykos Finland Oy (FI) 2011-05-18 EP disclosed
US-20060014672-A1 Tumor specific oligosaccharide epitopes and use thereof GLYKOS FINLAND OY (FI) 2006-01-19 US disclosed
EP-1534324-A2 TUMOR SPECIFIC OLIGOSACCHARIDE EPITOPES AND USE THEREOF BioTie Therapies Ltd. (FI) 2005-06-01 EP disclosed
WO-2004017810-A2 TUMOR SPECIFIC OLIGOSACCHARIDE EPITOPES AND USE THEREOF BIOTIE THERAPIES CORP. (FI) 2004-03-04 WO disclosed
EP-0487610-B1 PROHORMONE CLEAVAGE SITE BLOCKING ANTIBODY CHIRON CORP (US) 2000-02-09 EP disclosed
EP-0491828-B1 PEPTIDES FROM GTPase-ACTIVATING PROTEIN (GAP), DIAGNOSTIC AND THERAPEUTIC USE THEREOF CHIRON CORP (US) 1999-06-16 EP disclosed
WO-1989011548-A1 IMMOBILIZED SEQUENCE-SPECIFIC PROBES CETUS CORPORATION (US) 1989-11-30 WO disclosed
WO-1989011547-A1 METHOD FOR HLA DP TYPING CETUS CORPORATION (US) 1989-11-30 WO disclosed
WO-1989002932-A1 A COVALENT OLIGONUCLEOTIDE-HORSERADISH PEROXIDASE CONJUGATE CETUS CORPORATION (US) 1989-04-06 WO disclosed
WO-1989002931-A1 OLIGONUCLEOTIDE FUNCTIONALIZING REAGENTS AND METHODS CETUS CORPORATION (US) 1989-04-06 WO disclosed
EP-0305409-A1 SOLUBILIZATION OF PROTEINS FOR PHARMACEUTICAL COMPOSITIONS USING POLYPROLINE CONJUGATION. CETUS CORP (US) 1989-03-08 EP disclosed
US-4798787-A POLYCLONAL CETUS CORPORATION (US) 1989-01-17 US disclosed
US-4762706-A ANTICANCER CETUS CORPORATION (US) 1988-08-09 US disclosed
WO-1988003412-A1 SOLUBILIZATION OF PROTEINS FOR PHARMACEUTICAL COMPOSITIONS USING POLYPROLINE CONJUGATION CETUS CORPORATION (US) 1988-05-19 WO disclosed
EP-0177814-A2 Peptide antibodies and their use in detecting oncogene products CETUS CORPORATION (US) 1986-04-16 EP disclosed
EP-0175360-A2 Peptide antibodies and their use in detecting oncogene products CETUS CORPORATION (US) 1986-03-26 EP disclosed