Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5316785 | 0.85 | NPSR1 (0.62) | L3MBTL1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL18330454 | 0.85 | USP2 (0.47) | L3MBTL1KDM4EMEN1KMT2AUSP2 | |
| SCHEMBL12440445 | 0.84 | USP2 (0.54) | L3MBTL1KDM4EMEN1KMT2AUSP2 | |
| SCHEMBL18330504 | 0.81 | EPHX2 (0.57) | EPHX1EPHX2 | |
| SCHEMBL20061877 | 0.81 | KDM4E (0.45) | L3MBTL1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL13191363 | 0.81 | EPHX2 (0.53) | L3MBTL1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL12438989 | 0.81 | NPSR1 (0.59) | L3MBTL1MEN1KMT2AEPHX1USP2 | |
| SCHEMBL6003218 | 0.81 | NPSR1 (0.65) | L3MBTL1MEN1KMT2AEPHX1USP2 | |
| SCHEMBL14309155 | 0.80 | NPSR1 (0.68) | L3MBTL1MEN1KMT2AEPHX1USP2 | |
| SCHEMBL17730252 | 0.78 | USP2 (0.49) | L3MBTL1KDM4EMEN1KMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160368930-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2016-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160368930-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | KRAS, HRAS, NRAS | L3MBTL1 3338/4885KDM4E 3032/4885MEN1 2804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.