Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14309155 | 0.98 | NPSR1 (0.68) | NPSR1SMN1; SMN2USP2KMT2AMEN1 | |
| SCHEMBL12438989 | 0.96 | NPSR1 (0.59) | NPSR1SMN1; SMN2USP2KMT2AMEN1 | |
| SCHEMBL12440445 | 0.92 | USP2 (0.54) | NPSR1USP2KMT2AMEN1TSHR | |
| SCHEMBL17741000 | 0.90 | NPSR1 (0.62) | NPSR1KMT2AMEN1TSHRHSD17B10 | |
| SCHEMBL17730252 | 0.85 | USP2 (0.49) | NPSR1USP2KMT2AMEN1TSHR | |
| SCHEMBL17730249 | 0.85 | USP2 (0.49) | NPSR1USP2KMT2AMEN1TSHR | |
| SCHEMBL17741001 | 0.82 | NPSR1 (0.62) | NPSR1SMN1; SMN2EPHX1 | |
| SCHEMBL18330454 | 0.82 | USP2 (0.47) | NPSR1USP2KMT2AMEN1L3MBTL1 | |
| SCHEMBL18330481 | 0.81 | L3MBTL1 (0.49) | NPSR1SMN1; SMN2USP2KMT2AMEN1 | |
| SCHEMBL9123206 | 0.81 | NPSR1 (0.59) | NPSR1SMN1; SMN2KMT2AMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9598432-B2 | 2,4-pyrimidinediamine compounds and uses as anti-proliferative agents | RIGEL PHARMACEUTICALS, INC. (US) | 2017-03-21 | — | — | US | disclosed |
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |