Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 6/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18332279 | 0.91 | ALOX5 (0.39) | ALOX5NOD2NOD1HPGDPTGDR2 | |
| SCHEMBL18332169 | 0.90 | ALOX5 (0.38) | ALOX5NOD2NOD1HPGDPTGDR2 | |
| SCHEMBL16188501 | 0.83 | ALOX5 (0.39) | ALOX5NOD2NOD1KDM1AHPGD | |
| SCHEMBL10002783 | 0.83 | ALOX5 (0.39) | ALOX5NOD2NOD1KDM1AHPGD | |
| SCHEMBL10002784 | 0.83 | ALOX5 (0.39) | ALOX5NOD2NOD1KDM1AHPGD | |
| SCHEMBL18332221 | 0.82 | HRH3 (0.39) | ALOX5NOD2NOD1HPGDPTGDR2 | |
| SCHEMBL18331686 | 0.82 | ALOX5 (0.40) | ALOX5SOS1NOD2NOD1KDM1A | |
| SCHEMBL10003558 | 0.81 | GPR119 (0.42) | ALOX5 | |
| SCHEMBL16188499 | 0.81 | GPR119 (0.42) | ALOX5 | |
| SCHEMBL11931671 | 0.81 | HRH3 (0.39) | ALOX5NOD2NOD1HPGDPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016204261-A1 | AMINOPYRAZOLE DERIVATIVES | 中外製薬株式会社 | 2016-12-22 | — | — | WO | disclosed |