Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1831293 | 0.86 | ESR1 (0.35) | ESR1KCNH2CYP3A4TSHRPIK3CA | |
| SCHEMBL1829077 | 0.80 | JAK2 (0.35) | ESR1KCNH2CYP3A4MAPT | |
| SCHEMBL2161460 | 0.80 | TDP1 (0.40) | TSHRALDH1A1KMT2AMAPT | |
| SCHEMBL1831943 | 0.75 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL1838061 | 0.74 | SKP2 (0.36) | ALDH1A1MEN1KMT2AKLKB1MAPT | |
| SCHEMBL1832731 | 0.72 | LMNA (0.38) | CYP3A4TSHRALDH1A1KMT2AKLKB1 | |
| SCHEMBL1831398 | 0.71 | ESR1 (0.35) | ESR1KCNH2CYP3A4TSHRPIK3CA | |
| SCHEMBL2161221 | 0.70 | KLKB1 (0.35) | KLKB1L3MBTL1 | |
| SCHEMBL1833544 | 0.69 | HTR1A (0.33) | KLKB1 | |
| SCHEMBL2161248 | 0.68 | KLKB1 (0.37) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2318374-A2 | INSECTICIDAL BENZENEDICARBOXAMIDE DERIVATIVE | Bayer CropScience AG (DE) | 2011-05-11 | — | — | EP | disclosed |
| WO-2010012442-A2 | INSECTICIDAL BENZENEDICARBOXAMIDE DERIVATIVE | BAYER CROPSCIENCE AG (DE) | 2010-02-04 | — | — | WO | disclosed |