Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | DAO | P14920 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | FLT3 | P36888 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | DDO | Q99489 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10441468 | 0.84 | PDGFRB (0.58) | KDM4EDAOMAPTHPGDSRD5A2 | |
| SCHEMBL3836490 | 0.84 | FLT3 (0.50) | KDM4EDAOMAPTHPGDSRD5A2 | |
| SCHEMBL9378872 | 0.84 | FLT3 (0.50) | KDM4EDAOMAPTHPGDSRD5A2 | |
| SCHEMBL4265956 | 0.84 | PDGFRB (0.56) | KDM4EDAOMAPTHPGDSRD5A2 | |
| SCHEMBL30073611 | 0.84 | PDGFRB (0.56) | KDM4EDAOMAPTHPGDSRD5A2 | |
| SCHEMBL6586200 | 0.82 | KDM4E (0.50) | KDM4EDAOMAPTHPGDSRD5A2 | |
| SCHEMBL6470774 | 0.81 | FLT3 (0.47) | KDM4EDAOMAPTHPGDSRD5A2 | |
| SCHEMBL31561461 | 0.81 | FLT3 (0.61) | KDM4EDAOMAPTHPGDSRD5A2 | |
| SCHEMBL10343383 | 0.81 | FLT3 (0.47) | KDM4EDAOMAPTHPGDSRD5A2 | |
| SCHEMBL29020309 | 0.80 | IDO1 (0.57) | KDM4EDAOMAPTHPGDSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968272-B1 | USE OF INDOLE COMPOUNDS FOR FAT REDUCTION AND SKIN AND SOFT TISSUE TIGHTENING | ALEVERE MEDICAL CORP (US) | 2021-06-16 | — | — | EP | claimed |
| CN-110372566-B | Method for catalyzing rearrangement of indole carbonate by chiral 3, 4-diaminopyridine nitrogen-oxygen catalyst | 河南师范大学 | 2020-08-04 | — | — | CN | claimed |
| EP-2948454-B1 | TRIAZINE COMPOUNDS AND A PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENT & IND RES AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGISTRATION OF SOCIETI (IN) | 2017-05-31 | — | — | EP | claimed |
| EP-1970470-B1 | Chrome(VI)-free black passivates for surfaces containing zinc | ATOTECH DEUTSCHLAND GMBH (DE) | 2011-05-11 | — | — | EP | claimed |
| WO-2010026096-A1 | 7-(PIPERAZINE-1-YMETHYL)-1H-INDOLE-2-CARBOXYLIC ACID (PHENYL)-AMIDE DERIVATIVES AND ALLIED COMPOUNDS AS P38 MAP KINASE INHIBITORS FOR THE TREATMENT OF RESPIRATORY DISEASES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-03-11 | — | — | WO | claimed |
| EP-2149551-A1 | N-(indol-3-ylalkyl)-(hetero)arylamid derivatives as modulators of EP2 receptors | Bayer Schering Pharma AG (DE) | 2010-02-03 | — | — | EP | claimed |
| EP-1970470-A1 | Chrome(VI)-free black passivates for surfaces containing zinc | ATOTECH DEUTSCHLAND GMBH (DE) | 2008-09-17 | — | — | EP | claimed |
| WO-2008107039-A1 | CHROMIUM(VI)-FREE BLACK PASSIVATION OF SURFACES CONTAINING ZINC | ATOTECH DEUTSCHLAND GMBH (DE) | 2008-09-12 | — | — | WO | claimed |
| EP-0868535-B9 | METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES | QIAGEN GENOMICS INC (US) | 2007-05-09 | — | — | EP | claimed |
| EP-1689711-A1 | METHOD FOR PRODUCING N- 1-(S)-CARBALKOXY-3-PHENYLPROPYL|-S-ALANYL-2S, 3AR, 7AS-OCTAHYDROINDOL-2-CARBOXYLIC ACID COMPOUNDS | Azad Pharmaceutical Ingredients AG (CH) | 2006-08-16 | — | — | EP | claimed |
| EP-0743574-B1 | Migration imaging members | XEROX CORP (US) | 2000-12-27 | — | — | EP | claimed |
| EP-0743573-B1 | Method for obtaining image contrast migration imaging members | XEROX CORP (US) | 2000-09-06 | — | — | EP | claimed |
| EP-0673782-B1 | Recording sheets containing pyrrole, pyrrolidine, pyridine, piperidine, homopiperidine, quinoline, isoquinoline, quinuclidine, indole, and indazole compounds | XEROX CORP (US) | 2000-06-14 | — | — | EP | claimed |
| EP-0868535-B1 | METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES | RAPIGENE INC (US) | 2000-04-12 | — | — | EP | claimed |
| EP-0519971-B1 | NOVEL PHARMACEUTICALLY ACTIVE COMPOUNDS WHICH CAN BE FORMED FROM 1,3,4,6,7,8-HEXAHYDRO-2H-PYRIMIDO-(1,2-a)-PYRIMIDINE | INST SOZIAL MED FORSCHUNG SA (CH) | 1997-01-15 | — | — | EP | claimed |
| EP-0526708-A1 | Sulfonamide, preparation and use thereof as medicine and intermediate | F. HOFFMANN-LA ROCHE AG (CH) | 1993-02-10 | — | — | EP | claimed |
| EP-0308339-B1 | PROCESS FOR THE INDUSTRIAL PREPARATION OF PERHYDROINDOLE -2(2S,3AS,7AS)-CARBOXYLIC ACID, USE IN THE PREPARATION OF CARBOXYALKYL DIPEPTIDES | ADIR ET COMPAGNIE (FR) | 1992-05-06 | — | — | EP | claimed |
| EP-0308341-B1 | PROCESS FOR THE INDUSTRIAL SYNTHESIS OF PERINDOPRIL AND FOR ITS PRINCIPAL SYNTHESIS INTERMEDIATES | ADIR ET COMPAGNIE (FR) | 1990-12-12 | — | — | EP | claimed |
| EP-0117447-A1 | Cyclic peptides with somatostatin activity | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-09-05 | — | — | EP | claimed |
| EP-0043752-B1 | PYRANOINDOLE DERIVATIVE AND PROCESS FOR ITS PREPARATION | SOCIETE DE RECHERCHES INDUSTRIELLES S.O.R.I. Société anonyme dite: (FR) | 1984-06-13 | — | — | EP | claimed |