Monoethanolamine

Monoethanolamine

SCHEMBL1833264

CS(=O)(=O)O.NCCO

nearest known ligand 0.00

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Known targets — ChEMBL curated mechanism

ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol

The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Monoethanolamine SCHEMBL4709287 1.00 TSHR (0.53)
Dimethyl Sulfone SCHEMBL27847716 0.90
Ethylenediamine SCHEMBL9351771 0.86
Sulfuric Acid SCHEMBL1837317 0.86 TSHR (0.61)
Ethylenediamine SCHEMBL27481010 0.86 BLM (0.50)
Sulfuric Acid SCHEMBL700465 0.86
SCHEMBL11147220 0.85 APP (0.48)
Monoethanolamine SCHEMBL11144600 0.84 TSHR (0.50)
Sulfuric Acid SCHEMBL28363659 0.84 TSHR (0.50)
Sulfuric Acid SCHEMBL28788758 0.83 TSHR (0.57)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-56151727-A None JP disclosed
JP-58147424-A None JP disclosed
EP-3055453-B1 LIGNOCELLULOSIC MATERIALS CONTAINING DEFIBRILLATED CELLULOSE BASF SE (DE) 2023-11-22 EP disclosed
CN-117043137-A Eutectic mixture and liquid composition 株式会社大赛璐 2023-11-10 CN disclosed
US-10399246-B2 Method for producing lignocellulose materials BASF SE (DE) 2019-09-03 US disclosed
EP-3274143-B1 METHOD FOR MANUFACTURING WOODEN MATERIALS BASF SE (DE) 2019-08-28 EP disclosed
US-20180071945-A1 METHOD FOR PRODUCING SINGLE- OR MULTI-LAYER LIGNOCELLULOSE MATERIALS USING TRIALKYL PHOSPHATE BASF SE (DE) 2018-03-15 US disclosed
US-20180071946-A1 METHOD FOR PRODUCING LIGNOCELLULOSE MATERIALS BASF SE (DE) 2018-03-15 US disclosed
EP-3274143-A1 METHOD FOR PRODUCING LIGNOCELLULOSE MATERIALS BASF SE (DE) 2018-01-31 EP disclosed
EP-3274144-A1 METHOD FOR PRODUCING SINGLE- OR MULTI-LAYER LIGNOCELLULOSE MATERIALS USING TRIALKYL PHOSPHATE BASF SE (DE) 2018-01-31 EP disclosed
WO-2005097731-A2 IONIC LIQUIDS COMPRISING NITROGEN CONTAINING CATIONS THE UNIVERSITY OF YORK (GB) 2005-10-20 WO disclosed
EP-1144509-A2 EXTRUDABLE MASTERBATCH EASTMAN CHEMICAL COMPANY (US) 2001-10-17 EP disclosed
WO-2000036015-A2 EXTRUDABLE MASTERBATCH EASTMAN CHEMICAL COMPANY (US) 2000-06-22 WO disclosed
EP-0442948-A1 QUATERNARY AMMONIUM ANTISTATIC COMPOUNDS PPG INDUSTRIES, INC. (US) 1991-08-28 EP disclosed
WO-1990005129-A2 QUATERNARY AMMONIUM ANTISTATIC COMPOUNDS PPG INDUSTRIES, INC. (US) 1990-05-17 WO disclosed
JP-S58147424-A NOVEL OIL-FREE POLYESTER AND ITS PREPARATION NIPPON PAINT CO LTD 1983-09-02 JP disclosed
US-4368287-A POLYESTER CONTAINING AMINO-SULFONIC AMPHOIONIC GROUP NIPPON PAINT CO., LTD. (JP) 1983-01-11 US disclosed
US-4328143-A Aqueous coating composition NIPPON PAINT COMPANY, LTD. (JP) 1982-05-04 US disclosed
US-4322324-A Ampho-ionic group-containing alkyd resins NIPPON PAINT CO., LTD. (JP) 1982-03-30 US disclosed
JP-S56151727-A NOVEL OIL FREE-POLYESTER AND ITS PREPARATION NIPPON PAINT CO LTD 1981-11-24 JP disclosed