Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | HPD | P32754 | 5/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | TDO2 | P48775 | 2/20 | 0.52 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22238067 | 0.92 | POLB (0.72) | POLBHPDHSD17B10SMN1; SMN2L3MBTL1 | |
| SCHEMBL31196718 | 0.91 | HPD (0.61) | POLBHPDHSD17B10SMN1; SMN2L3MBTL1 | |
| SCHEMBL31196727 | 0.91 | POLB (0.61) | POLBHPDHSD17B10SMN1; SMN2L3MBTL1 | |
| SCHEMBL31196714 | 0.91 | POLB (0.61) | POLBHPDHSD17B10SMN1; SMN2L3MBTL1 | |
| SCHEMBL29110466 | 0.91 | HSD17B10 (0.72) | POLBHPDHSD17B10SMN1; SMN2L3MBTL1 | |
| SCHEMBL30089880 | 0.91 | HSD17B10 (0.72) | POLBHPDHSD17B10SMN1; SMN2L3MBTL1 | |
| SCHEMBL31196719 | 0.90 | HPD (0.59) | POLBHPDHSD17B10SMN1; SMN2L3MBTL1 | |
| SCHEMBL29839760 | 0.89 | HSD17B10 (0.73) | POLBHPDHSD17B10SMN1; SMN2L3MBTL1 | |
| SCHEMBL29839759 | 0.89 | HSD17B10 (0.73) | POLBHPDHSD17B10SMN1; SMN2L3MBTL1 | |
| SCHEMBL20081376 | 0.85 | HPD (0.49) | POLBHPDL3MBTL1TDO2IDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705287-A1 | SMALL MOLECULE HUMANIN MIMETICS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024226731-A1 | SMALL MOLECULE HUMANIN MIMETICS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-10-31 | — | — | WO | disclosed |
| EP-3312175-A1 | HETEROARYL DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING DISEASES ASSOCIATED WITH PI3 KINASES, CONTAINING SAME AS ACTIVE INGREDIENT | Korea Research Institute of Chemical Technology (KR) | 2018-04-25 | — | — | EP | disclosed |
| WO-2016204429-A1 | HETEROARYL DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING DISEASES ASSOCIATED WITH PI3 KINASES, CONTAINING SAME AS ACTIVE INGREDIENT | 한국화학연구원 | 2016-12-22 | — | — | WO | disclosed |