Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.66 |
| ▸ | GLA | P06280 | 1/20 | 0.66 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HPD | P32754 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29839759 | 1.00 | HSD17B10 (0.73) | HSD17B10SMN1; SMN2POLBL3MBTL1GLA | |
| SCHEMBL18332822 | 0.89 | POLB (0.65) | HSD17B10SMN1; SMN2POLBL3MBTL1GLA | |
| SCHEMBL1962312 | 0.86 | HSD17B10 (0.77) | HSD17B10SMN1; SMN2POLBL3MBTL1ALOX12 | |
| SCHEMBL22238128 | 0.85 | USP2 (0.59) | HSD17B10SMN1; SMN2L3MBTL1GLAALDH1A1 | |
| SCHEMBL31196718 | 0.85 | HPD (0.61) | HSD17B10SMN1; SMN2POLBL3MBTL1GLA | |
| SCHEMBL30122631 | 0.85 | MAPK1 (0.75) | HSD17B10SMN1; SMN2POLBL3MBTL1ALOX12 | |
| SCHEMBL1682746 | 0.85 | MAPK1 (0.75) | HSD17B10SMN1; SMN2POLBL3MBTL1ALOX12 | |
| SCHEMBL29154650 | 0.84 | HSD17B10 (0.75) | HSD17B10SMN1; SMN2POLBL3MBTL1ALOX12 | |
| SCHEMBL30726096 | 0.84 | HSD17B10 (0.75) | HSD17B10SMN1; SMN2POLBL3MBTL1ALOX12 | |
| SCHEMBL30726097 | 0.84 | HSD17B10 (0.75) | HSD17B10SMN1; SMN2POLBL3MBTL1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907479-B | Anti-CD 112R antibodies and uses thereof | 上海君实生物医药科技股份有限公司 | 2024-12-31 | — | — | CN | disclosed |
| US-20240309087-A1 | ANTI-CD112R ANTIBODY AND USE THEREOF | SHANGHAI JUNSHI BIOSCIENCES CO., LTD. (CN) | 2024-09-19 | — | — | US | disclosed |
| WO-2022171080-A1 | ANTI-CD112R ANTIBODY AND USE THEREOF | 上海君实生物医药科技股份有限公司 | 2022-08-18 | — | — | WO | disclosed |
| CN-114907479-A | anti-CD 112R antibodies and uses thereof | 上海君实生物医药科技股份有限公司 | 2022-08-16 | — | — | CN | disclosed |