SCHEMBL183337

SCHEMBL183337

CCCC(=O)C(=O)OC(C)=O

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CES1 P23141 7/20 0.52
CES2 O00748 6/20 0.52
ALDH1A1 P00352 5/20 0.46
TSHR P16473 2/20 0.43
FFAR3 O14843 3/20 0.42
HDAC3 O15379 3/20 0.42
HDAC1 Q13547 3/20 0.42
HDAC2 Q92769 3/20 0.42
HDAC8 Q9BY41 3/20 0.42
TDP1 Q9NUW8 2/20 0.36
HSD17B10 Q99714 2/20 0.36
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6929642 0.98 CES1 (0.50) CES1CES2ALDH1A1TSHRFFAR3
SCHEMBL28442996 0.87 CES2 (0.61) CES1CES2ALDH1A1TSHRFFAR3
SCHEMBL27977518 0.84 CES1 (0.58) CES1CES2ALDH1A1TSHRTDP1
SCHEMBL27977810 0.82 CES1 (0.56) CES1CES2ALDH1A1TSHRTDP1
SCHEMBL28006875 0.82 CES1 (0.60) CES1CES2ALDH1A1TSHRTDP1
SCHEMBL27977828 0.82 CES1 (0.56) CES1CES2ALDH1A1TSHRTDP1
SCHEMBL20031080 0.82 CES1 (0.44) CES1CES2ALDH1A1TSHRFFAR3
SCHEMBL27977807 0.82 CES1 (0.56) CES1CES2ALDH1A1TSHRTDP1
SCHEMBL28813498 0.82 CES1 (0.56) CES1CES2ALDH1A1TSHRTDP1
SCHEMBL27977802 0.82 CES1 (0.56) CES1CES2ALDH1A1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12612400-B2 Pyrrolopyridine derivative preparation method ST PHARM CO., LTD. (KR) 2026-04-28 US claimed
EP-4276101-B1 PYRROLOPYRIDINE DERIVATIVE PREPARATION METHOD ST PHARM CO LTD (KR) 2026-03-04 EP claimed
US-20240317737-A1 PYRROLOPYRIDINE DERIVATIVE PREPARATION METHOD ST PHARM CO., LTD. (KR) 2024-09-26 US claimed
EP-4276101-A1 PYRROLOPYRIDINE DERIVATIVE PREPARATION METHOD ST Pharm Co., Ltd. (KR) 2023-11-15 EP claimed
CN-109896684-A A kind of pre-treating process for sewage in organic products preparation process 李德祥 2019-06-18 CN claimed
CN-108359514-A A kind of high-performance environment protection type lubricating oil and preparation method thereof 合肥择浚电气设备有限公司 2018-08-03 CN claimed
CN-105800766-B Carbon tetrachloride device and its method of work in a kind of high temperature aeration removal underground water 徐州市城区水资源管理处 2018-06-15 CN claimed
CN-106635311-A Novel lubricating oil and preparation method thereof 苏州圣鑫莱新材料有限公司 2017-05-10 CN claimed
CN-106587907-A Energy-saving and environment-protection decoration plate used for building decoration engineering, and production method thereof 天津尔东科技有限公司 2017-04-26 CN claimed
CN-105800766-A Device for removing carbon tetrachloride in underground water through high temperature aeration and working method thereof 徐州市城区水资源管理处 2016-07-27 CN claimed
CN-104893154-A Environmentally-friendly 90-DEG C polyvinyl chloride cable insulating material YANTAI SHUNLONG CHEMICAL TECHNOLOGY CO LTD 2015-09-09 CN claimed
CN-104830408-A Emulsified metal cutting fluid YANTAI SHUNLONG CHEMICAL ENGINEERING TECHNOLOGY CO LTD 2015-08-12 CN claimed
CN-102976942-A Preparation method of acetyl ethyl pyruvate UNIV ZHEJIANG TECHNOLOGY 2013-03-20 CN claimed
CN-102971261-A Silica remediation in water GEN ELECTRIC 2013-03-13 CN claimed
US-12612400-B2 Pyrrolopyridine derivative preparation method ST PHARM CO., LTD. (KR) 2026-04-28 US disclosed
EP-4276101-B1 PYRROLOPYRIDINE DERIVATIVE PREPARATION METHOD ST PHARM CO LTD (KR) 2026-03-04 EP disclosed
EP-3745105-B1 TEMPERATURE DETECTION LABEL AND ARTICLE MANAGEMENT DEVICE USING SAME HITACHI LTD (JP) 2025-08-27 EP disclosed
US-4214090-A Fungicidal carboxamidopyrazoles COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AT) 1980-07-22 US disclosed
EP-0000541-A2 1H-Pyrimido-(4,5-c)-1,2-diazepines, methods for their preparation and compositions containing them; their use as intermediates for heterocyclic transformations. THE WELLCOME FOUNDATION LIMITED (GB) 1979-02-07 EP disclosed
US-4134987-A PYRAZOLE DERIVATIVES, FUNGICIDES HUPPATZ JOHN L 1979-01-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240317737-A1 PYRROLOPYRIDINE DERIVATIVE PREPARATION METHOD MAVS, DPYD, ITPA CES1 2019/4885CES2 1292/4885ALDH1A1 2350/4885
US-12612400-B2 Pyrrolopyridine derivative preparation method PNP, MAP2K4, MAP2K5 CES1 92/4885CES2 599/4885ALDH1A1 686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.