Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18334656 | 1.00 | ALDH1A1 (0.54) | ALDH1A1MAPK1L3MBTL1KMT2ATDP1 | |
| SCHEMBL18334359 | 0.91 | ALDH1A1 (0.51) | ALDH1A1MAPK1L3MBTL1KMT2ATDP1 | |
| SCHEMBL18334358 | 0.91 | ALDH1A1 (0.51) | ALDH1A1MAPK1L3MBTL1KMT2ATDP1 | |
| SCHEMBL18803445 | 0.88 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1KMT2ATDP1 | |
| SCHEMBL18334350 | 0.88 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1KMT2ATDP1 | |
| SCHEMBL18334351 | 0.88 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1KMT2ATDP1 | |
| SCHEMBL18334381 | 0.86 | ALDH1A1 (0.50) | ALDH1A1MAPK1L3MBTL1KMT2ATDP1 | |
| SCHEMBL18334380 | 0.86 | ALDH1A1 (0.50) | ALDH1A1MAPK1L3MBTL1KMT2ATDP1 | |
| SCHEMBL28277844 | 0.85 | ALDH1A1 (0.59) | ALDH1A1MAPK1L3MBTL1KMT2ATDP1 | |
| SCHEMBL18334330 | 0.83 | ALDH1A1 (0.58) | ALDH1A1MAPK1L3MBTL1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3109230-B1 | CLASS OF CARBOXYLIC ACID DERIVATIVES AND USE THEREOF IN PREPARATION OF PRODRUGS | LI QINGENG (CN) | 2019-11-20 | — | — | EP | claimed |
| US-10239851-B2 | Carboxylic acid derivatives and use thereof in the preparation of prodrugs | Li, Qingeng (CN) | 2019-03-26 | — | — | US | claimed |
| US-20170057939-A1 | CARBOXYLIC ACID DERIVATIVES AND USE THEREOF IN THE PREPARATION OF PRODRUGS | LI, Qingeng (CN) | 2017-03-02 | — | — | US | claimed |
| EP-3109230-B1 | CLASS OF CARBOXYLIC ACID DERIVATIVES AND USE THEREOF IN PREPARATION OF PRODRUGS | LI QINGENG (CN) | 2019-11-20 | — | — | EP | disclosed |
| US-10239851-B2 | Carboxylic acid derivatives and use thereof in the preparation of prodrugs | Li, Qingeng (CN) | 2019-03-26 | — | — | US | disclosed |
| US-9643917-B2 | Water-soluble propofol derivatives and uses thereof | JIANGSU NHWALUOKANG PHARMCEUTICAL RESEARCH AND DEVELOPMENT CO., LTD (CN) | 2017-05-09 | — | — | US | disclosed |
| US-20170057939-A1 | CARBOXYLIC ACID DERIVATIVES AND USE THEREOF IN THE PREPARATION OF PRODRUGS | LI, Qingeng (CN) | 2017-03-02 | — | — | US | disclosed |
| EP-3109230-A1 | CLASS OF CARBOXYLIC ACID DERIVATIVES AND USE THEREOF IN PREPARATION OF PRODRUGS | Li, Qingeng (CN) | 2016-12-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10239851-B2 | Carboxylic acid derivatives and use thereof in the preparation of prodrugs | NR4A3, HCAR3, FFAR3 | ALDH1A1 932/4885MAPK1 2962/4885L3MBTL1 4064/4885 |
| US-20170057939-A1 | CARBOXYLIC ACID DERIVATIVES AND USE THEREOF IN THE PREPARATION OF PRODRUGS | NR4A3, HCAR3, NR4A2 | ALDH1A1 897/4885MAPK1 2921/4885L3MBTL1 4039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.