Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 5/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | PTGES | O14684 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18335132 | 0.93 | EGLN1 (0.36) | P2RX7EGLN1IRAK4DRD2DRD3 | |
| SCHEMBL18335139 | 0.92 | EGLN1 (0.37) | P2RX7EGLN1IRAK4DRD2DRD3 | |
| SCHEMBL18335165 | 0.81 | EGLN1 (0.38) | P2RX7EGLN1DRD2DRD3PTGES | |
| SCHEMBL18335095 | 0.77 | EGLN1 (0.39) | EGLN1IRAK4DRD3PTGES | |
| SCHEMBL18335072 | 0.73 | P2RX7 (0.38) | P2RX7EGLN1IRAK4 | |
| SCHEMBL18335159 | 0.72 | ACACB (0.34) | EGLN1IRAK4PTGES | |
| SCHEMBL18335085 | 0.71 | CHRNB2 (0.38) | EGLN1 | |
| SCHEMBL18335091 | 0.71 | P2RX7 (0.41) | P2RX7EGLN1PTGES | |
| SCHEMBL18335152 | 0.70 | EGLN1 (0.39) | EGLN1IRAK4DRD3PTGES | |
| SCHEMBL18335160 | 0.69 | ACACB (0.33) | EGLN1PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10029986-B2 | Alkynyl pyridine-substituted amide compound and pesticide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2018-07-24 | — | — | US | disclosed |
| US-20170008847-A1 | ALKYNYL PYRIDINE-SUBSTITUTED AMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-01-12 | — | — | US | disclosed |
| EP-3109234-A1 | ALKYNYLPYRIDINE-SUBSTITUTED AMIDE COMPOUND AND NOXIOUS ORGANISM CONTROL AGENT | Nissan Chemical Industries, Ltd. (JP) | 2016-12-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10029986-B2 | Alkynyl pyridine-substituted amide compound and pesticide | CHRM1, CHRM2, CHRM3 | P2RX7 432/4885EGLN1 1022/4885IRAK4 4284/4885 |
| US-20170008847-A1 | ALKYNYL PYRIDINE-SUBSTITUTED AMIDE COMPOUND AND PESTICIDE | CHRM1, CHRM2, CHRM3 | P2RX7 432/4885EGLN1 1022/4885IRAK4 4284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.