SCHEMBL1834175

SCHEMBL1834175

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nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PGD P52209 1/20 0.33
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
PDE4A P27815 1/20 0.31
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1837982 0.91 PDE4A (0.33) ALDH1A1TSHRPDE4A
SCHEMBL1830209 0.76 TSHR (0.47) PGDALDH1A1TSHRPDE4ATP53
SCHEMBL17887907 0.73 TSHR (0.50) ALDH1A1TSHRPDE4ATP53
SCHEMBL7148974 0.73 TSHR (0.50) ALDH1A1TSHRPDE4ATP53
SCHEMBL1832088 0.73 TSHR (0.50) ALDH1A1TSHRPDE4ATP53
SCHEMBL12904430 0.73 TSHR (0.50) ALDH1A1TSHRPDE4ATP53
SCHEMBL11059297 0.73 TSHR (0.50) ALDH1A1TSHRPDE4ATP53
SCHEMBL265598 0.73 TSHR (0.50) ALDH1A1TSHRPDE4ATP53
SCHEMBL19127751 0.73 TSHR (0.50) ALDH1A1TSHRPDE4ATP53
SCHEMBL29709585 0.73 TSHR (0.50) ALDH1A1TSHRPDE4ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0780399-B1 Glucuronylarabinarates, process for their preparation and uses of these products ROQUETTE FRERES (FR) 2001-06-20 EP claimed
EP-0780399-A2 Glucuronylarabinarates, process for their preparation and uses of these products Roquette Frˬres (FR) 1997-06-25 EP claimed
EP-1540038-B1 METHOD FOR PREPARING A POLYCARBOXYLIC COMPOSITION COMPRISING AN ELECTROCHEMICAL OXIDATION STAGE OF A MONOSACCHARIDE COMPOSITION ROQUETTE FRERES (FR) 2011-05-11 EP disclosed
US-7728170-B2 Method for preparing a polycarboxylic composition comprising an electrochemical oxidation stage of a monosaccharide composition ROQUETTE FRERES (FR) 2010-06-01 US disclosed
US-20050252785-A1 Method for preparing a polycarboxylic composition comprising an electrochemical oxidation stage of a monosaccharide composition ROQUETTE FRERES (FR) 2005-11-17 US disclosed
EP-1540038-A1 METHOD FOR PREPARING A POLYCARBOXYLIC COMPOSITION COMPRISING AN ELECTROCHEMICAL OXIDATION STAGE OF A MONOSACCHARIDE COMPOSITION Roquette Frˬres (FR) 2005-06-15 EP disclosed
WO-2004027118-A1 METHOD FOR PREPARING A POLYCARBOXYLIC COMPOSITION COMPRISING AN ELECTROCHEMICAL OXIDATION STAGE OF A MONOSACCHARIDE COMPOSITION ROQUETTE FRERES (FR) 2004-04-01 WO disclosed
EP-0798310-B1 Improved process for the oxidation of sugars ROQUETTE FRERES (FR) 2002-04-24 EP disclosed
EP-0780399-B1 Glucuronylarabinarates, process for their preparation and uses of these products ROQUETTE FRERES (FR) 2001-06-20 EP disclosed
EP-0780399-B1 Glucuronylarabinarates, process for their preparation and uses of these products ROQUETTE FRERES (FR) 2001-06-20 EP disclosed
US-5981742-A OXIDATIVE ALKALINE DEGRADATION OF STARCH HYDROLYSATE ROQUETTE FRERES (FR) 1999-11-09 US disclosed
EP-0780399-A3 Glucuronylarabinarates, process for their preparation and uses of these products Roquette Frˬres (FR) 1998-03-18 EP disclosed
EP-0780399-A3 Glucuronylarabinarates, process for their preparation and uses of these products Roquette Frˬres (FR) 1998-03-18 EP disclosed
EP-0798310-A1 Improved process for the oxidation of sugars Roquette Frˬres (FR) 1997-10-01 EP disclosed
EP-0780399-A2 Glucuronylarabinarates, process for their preparation and uses of these products Roquette Frˬres (FR) 1997-06-25 EP disclosed
EP-0780399-A2 Glucuronylarabinarates, process for their preparation and uses of these products Roquette Frˬres (FR) 1997-06-25 EP disclosed
EP-0780399-A2 Glucuronylarabinarates, process for their preparation and uses of these products Roquette Frˬres (FR) 1997-06-25 EP disclosed