SCHEMBL1837982

SCHEMBL1837982

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nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.33
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1834175 0.91 PGD (0.33) PDE4AALDH1A1TSHR
SCHEMBL5356598 0.79 TSHR (0.43) PDE4ATSHR
SCHEMBL722150 0.79 TSHR (0.43) PDE4ATSHR
SCHEMBL17887907 0.77 TSHR (0.50) PDE4AALDH1A1TSHR
SCHEMBL265598 0.77 TSHR (0.50) PDE4AALDH1A1TSHR
SCHEMBL11059297 0.77 TSHR (0.50) PDE4AALDH1A1TSHR
SCHEMBL1832088 0.77 TSHR (0.50) PDE4AALDH1A1TSHR
SCHEMBL7148974 0.77 TSHR (0.50) PDE4AALDH1A1TSHR
SCHEMBL12904430 0.77 TSHR (0.50) PDE4AALDH1A1TSHR
SCHEMBL19127751 0.77 TSHR (0.50) PDE4AALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0798310-B1 Improved process for the oxidation of sugars ROQUETTE FRERES (FR) 2002-04-24 EP claimed
EP-0798310-A1 Improved process for the oxidation of sugars Roquette Frˬres (FR) 1997-10-01 EP claimed
EP-1540038-B1 METHOD FOR PREPARING A POLYCARBOXYLIC COMPOSITION COMPRISING AN ELECTROCHEMICAL OXIDATION STAGE OF A MONOSACCHARIDE COMPOSITION ROQUETTE FRERES (FR) 2011-05-11 EP disclosed
US-7728170-B2 Method for preparing a polycarboxylic composition comprising an electrochemical oxidation stage of a monosaccharide composition ROQUETTE FRERES (FR) 2010-06-01 US disclosed
US-20050252785-A1 Method for preparing a polycarboxylic composition comprising an electrochemical oxidation stage of a monosaccharide composition ROQUETTE FRERES (FR) 2005-11-17 US disclosed
EP-0798310-B1 Improved process for the oxidation of sugars ROQUETTE FRERES (FR) 2002-04-24 EP disclosed
EP-0780399-B1 Glucuronylarabinarates, process for their preparation and uses of these products ROQUETTE FRERES (FR) 2001-06-20 EP disclosed
US-5831043-A Process for the oxidation of sugars Freres, Roquette (FR) 1998-11-03 US disclosed
EP-0798310-A1 Improved process for the oxidation of sugars Roquette Frˬres (FR) 1997-10-01 EP disclosed
EP-0780399-A2 Glucuronylarabinarates, process for their preparation and uses of these products Roquette Frˬres (FR) 1997-06-25 EP disclosed