Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.58 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5815460 | 0.98 | EPHX1 (0.66) | EPHX1ALDH1A1USP2HPGDSMN1; SMN2 | |
| SCHEMBL28499155 | 0.94 | MTNR1A (0.61) | EPHX1ALDH1A1USP2HPGDEPHX2 | |
| SCHEMBL3392745 | 0.89 | ALDH1A1 (0.74) | EPHX1ALDH1A1USP2HPGDSMN1; SMN2 | |
| SCHEMBL13138659 | 0.89 | ALDH1A1 (0.74) | EPHX1ALDH1A1USP2HPGDSMN1; SMN2 | |
| SCHEMBL12420662 | 0.87 | MTNR1A (0.56) | EPHX1ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL17117245 | 0.87 | POLB (0.59) | EPHX1ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL13746185 | 0.84 | CYP2C19 (0.62) | ALDH1A1HPGDLMNAFKBP1ACYP2C19 | |
| SCHEMBL23417495 | 0.83 | CYP2C19 (0.68) | ALDH1A1USP2HPGDSMN1; SMN2LMNA | |
| SCHEMBL26109813 | 0.82 | KMT2A (0.56) | EPHX1ALDH1A1HPGDFKBP1ACYP2C19 | |
| SCHEMBL26110422 | 0.82 | KMT2A (0.56) | EPHX1ALDH1A1HPGDFKBP1ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016209926-A1 | CANCERS EXPRESSING CCR5 AND METHODS OF TREATMENT OF SAME | THOMAS JEFFERSON UNIVERSITY (US) | 2016-12-29 | — | — | WO | claimed |