Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGM | P11217 | 3/20 | 0.52 |
| ▸ | CDA | P32320 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.49 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.49 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.49 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MTOR | P42345 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27652070 | 0.83 | CDA (0.38) | PYGMCDAMAPTSLC28A1SLC28A2 | |
| SCHEMBL28612080 | 0.79 | CDA (0.52) | PYGMCDAMAPTSLC28A1SLC28A2 | |
| SCHEMBL20211428 | 0.79 | CDA (0.52) | PYGMCDAMAPTSLC28A1SLC28A2 | |
| SCHEMBL26099251 | 0.78 | CDA (0.49) | PYGMCDAMAPTSLC28A1SLC28A2 | |
| SCHEMBL25866953 | 0.72 | OGA (0.46) | SLC28A3ALDH1A1 | |
| SCHEMBL7023712 | 0.71 | SLC28A1 (0.55) | PYGMCDAMAPTSLC28A1SLC28A2 | |
| SCHEMBL7023707 | 0.71 | SLC28A1 (0.55) | PYGMCDAMAPTSLC28A1SLC28A2 | |
| SCHEMBL29359502 | 0.71 | CDA (0.46) | PYGMCDAMAPTSLC28A1SLC28A2 | |
| SCHEMBL31509115 | 0.71 | SLC28A1 (0.51) | PYGMCDAMAPTSLC28A1SLC28A2 | |
| SCHEMBL31685710 | 0.70 | LMNA (0.42) | CDAMAPTSLC28A1SLC28A2SLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3313200-B1 | (5R)-(SS-D-GLUCOPYRANOSYLOXY)-1,5-DIHYDRO-2H-PYRROL-2-ONE AS UMAMI MOLECULE | NESTEC SA (CH) | 2019-04-03 | — | — | EP | disclosed |
| US-20180153203-A1 | (5R)-(ß-D-GLUCOPYRANOSYLOXY)-1,5-DIHYDRO-2H-PYRROL-2-ONE AS UMAMI MOLECULE | Société des Produits Nestlé S.A. (CH) | 2018-06-07 | — | — | US | disclosed |
| EP-3313200-A1 | (5R)-(ß-D-GLUCOPYRANOSYLOXY)-1,5-DIHYDRO-2H | Nestec S.A. (CH) | 2018-05-02 | — | — | EP | disclosed |
| WO-2016207174-A1 | (5R)-(ß-D-GLUCOPYRANOSYLOXY)-1,5-DIHYDRO-2H-PYRROL-2- ONE AS UMAMI MOLECULE | NESTEC S.A. (CH) | 2016-12-29 | — | — | WO | disclosed |