SCHEMBL7023712

SCHEMBL7023712

O=c1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.55
SLC28A2 O43868 1/20 0.55
SLC29A1 Q99808 1/20 0.55
SLC28A3 Q9HAS3 1/20 0.55
CDA P32320 4/20 0.52
MAPT P10636 1/20 0.52
LMNA P02545 3/20 0.52
MTOR P42345 2/20 0.52
THRB P10828 1/20 0.52
MDM2 Q00987 1/20 0.52
NCOA1 Q15788 1/20 0.52
NCOA3 Q9Y6Q9 1/20 0.52
PYGM P11217 3/20 0.48
SMN1; SMN2 Q16637 2/20 0.46
ALDH1A1 P00352 2/20 0.46
POLB P06746 1/20 0.46
GMNN O75496 1/20 0.46
TP53 P04637 1/20 0.46
NFKB1 P19838 1/20 0.46
DNMT1 P26358 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7023707 1.00 SLC28A1 (0.55) SLC28A1SLC28A2SLC29A1SLC28A3CDA
SCHEMBL24487856 0.86 CDA (0.51) SLC28A1SLC28A2SLC29A1SLC28A3CDA
SCHEMBL2845039 0.80 CDA (0.51) SLC28A1SLC28A2SLC29A1SLC28A3CDA
SCHEMBL14570585 0.80 MAPT (0.53) SLC28A1SLC28A2SLC29A1SLC28A3CDA
SCHEMBL7033026 0.80 MAPT (0.53) SLC28A1SLC28A2SLC29A1SLC28A3CDA
SCHEMBL5954124 0.80 MAPT (0.53) SLC28A1SLC28A2SLC29A1SLC28A3CDA
SCHEMBL10243962 0.80 MAPT (0.53) SLC28A1SLC28A2SLC29A1SLC28A3CDA
SCHEMBL28163188 0.79 MAPT (0.50) SLC28A1SLC28A2SLC29A1SLC28A3CDA
SCHEMBL28049721 0.79 MAPT (0.50) SLC28A1SLC28A2SLC29A1SLC28A3CDA
SCHEMBL28121628 0.79 MAPT (0.50) SLC28A1SLC28A2SLC29A1SLC28A3CDA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE TEAM MEDICAL, LLC 2025-09-18 US disclosed
US-20230365970-A1 Modified Short Interfering Nucleic Acid (siNA) Molecules and Uses Thereof ALIGOS THERAPEUTICS, INC. (US) 2023-11-16 US disclosed
US-20230332153-A1 Modified Short Interfering Nucleic Acid (siNA) Molecules and Uses Thereof ALIGOS THERAPEUTICS, INC. (US) 2023-10-19 US disclosed
US-20030144489-A1 Method for screening nucleic acid catalysts RIBOZYME PHARMACEUTICALS, INC. 2003-07-31 US disclosed
EP-1321521-A1 Ribozymes directed against flt-1 RIBOZYME PHARMACEUTICALS, INC. (US) 2003-06-25 EP disclosed
US-6548657-B1 Synthesis of ribozyme libraries and gene sequences RIBOZYME PHARMACEUTICALS, INC. 2003-04-15 US disclosed
US-6280936-B1 USEFUL FOR CLEAVAGE OF RIBONUCLEIC ACID (RNA) AND DEOXYRIBONUCLEIC ACID RIBOZYME PHARMACEUTICALS, INC. 2001-08-28 US disclosed
WO-1998050530-A9 ENZYMATIC NUCLEIC ACIDS: SYNTHESIS, SELECTION AND USE RIBOZYME PHARM INC (US) 1999-03-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230365970-A1 Modified Short Interfering Nucleic Acid (siNA) Molecules and Uses Thereof NSUN2, SNRPA, SNRPF SLC28A1 204/4885SLC28A2 183/4885SLC29A1 666/4885
US-20230332153-A1 Modified Short Interfering Nucleic Acid (siNA) Molecules and Uses Thereof NSUN2, SNRPA, SNRPF SLC28A1 204/4885SLC28A2 183/4885SLC29A1 666/4885
US-20030144489-A1 Method for screening nucleic acid catalysts POLM, POLRMT, RNGTT SLC28A1 1028/4885SLC28A2 893/4885SLC29A1 677/4885
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE SYNCRIP, SNRPA, RNASE1 SLC28A1 2343/4885SLC28A2 2401/4885SLC29A1 1381/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.