⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2252392 | 0.67 | — | — | |
| SCHEMBL1413367 | 0.59 | — | — | |
| SCHEMBL244747 | 0.59 | — | — | |
| SCHEMBL12275635 | 0.57 | — | — | |
| SCHEMBL6741324 | 0.56 | — | — | |
| Fluoride SCHEMBL8841037 | 0.56 | — | — | |
| SCHEMBL7053562 | 0.56 | — | — | |
| SCHEMBL12569520 | 0.56 | — | — | |
| SCHEMBL30059 | 0.56 | — | — | |
| SCHEMBL363537 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4411450-A | PRESSURE-SENSITIVE OR HEAT-SENSITIVE RECORDING MATERIAL | CIBA-GEIGY CORPORATION (US) | 1983-10-25 | — | — | US | claimed |
| US-4287336-A | Chromogenic propenylenesulfone compounds | CIBA-GEIGY CORPORATION (US) | 1981-09-01 | — | — | US | claimed |
| EP-2318377-B1 | PYRIMIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | GENENTECH INC (US) | 2013-08-21 | — | — | EP | disclosed |
| US-20120165313-A1 | PYRIMIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | GENENTECH, INC. (US) | 2012-06-28 | — | — | US | disclosed |
| US-8163763-B2 | Pyrimidine compounds, compositions and methods of use | GENENTECH, INC. (US) | 2012-04-24 | — | — | US | disclosed |
| EP-2318377-A1 | PYRIMIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | Genentech, Inc. (US) | 2011-05-11 | — | — | EP | disclosed |
| US-20100069357-A1 | PYRIMIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | GENENTECH, INC. (US) | 2010-03-18 | — | — | US | disclosed |
| WO-2010014939-A1 | PYRIMIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | GENENTECH, INC. (US) | 2010-02-04 | — | — | WO | disclosed |
| WO-2007125236-A1 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE ELECTROPHILIC MONOMER AND AT LEAST ONE CROSS-LINKED ELASTOMER ORGANOPOLYSILOXANE | L'OREAL (FR) | 2007-11-08 | — | — | WO | disclosed |
| US-4895954-A | Dyeing wool, cellulose | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-01-23 | — | — | US | disclosed |
| US-4411450-A | PRESSURE-SENSITIVE OR HEAT-SENSITIVE RECORDING MATERIAL | CIBA-GEIGY CORPORATION (US) | 1983-10-25 | — | — | US | disclosed |
| US-4411450-A | PRESSURE-SENSITIVE OR HEAT-SENSITIVE RECORDING MATERIAL | CIBA-GEIGY CORPORATION (US) | 1983-10-25 | — | — | US | disclosed |
| US-4287336-A | Chromogenic propenylenesulfone compounds | CIBA-GEIGY CORPORATION (US) | 1981-09-01 | — | — | US | disclosed |
| US-4287336-A | Chromogenic propenylenesulfone compounds | CIBA-GEIGY CORPORATION (US) | 1981-09-01 | — | — | US | disclosed |