Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | TYMS | P04818 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | HTR5A | P47898 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18347005 | 0.89 | ADORA2A (0.38) | CYP1A2DHODHADORA2AADORA1HTR2B | |
| SCHEMBL17035158 | 0.86 | CYP1A2 (0.47) | CYP1A2BACE1DHODHADORA2ATYMS | |
| SCHEMBL18200645 | 0.86 | MAPK8 (0.43) | DHODHADORA2AADORA1HTR2BHTR5A | |
| SCHEMBL18200633 | 0.84 | MAPK8 (0.42) | DHODHADORA2AADORA1HTR2BHTR5A | |
| SCHEMBL18347047 | 0.83 | BIRC5 (0.47) | CYP1A2ADORA2AADORA1KDM4EMEN1 | |
| SCHEMBL18346929 | 0.83 | MET (0.40) | CYP1A2DHODHADORA2AADORA1ALDH1A1 | |
| SCHEMBL18200401 | 0.83 | MET (0.40) | CYP1A2DHODHADORA2AADORA1HTR2B | |
| SCHEMBL21537832 | 0.82 | CYP2A6 (0.43) | CYP1A2KDM4EMEN1KMT2A | |
| SCHEMBL18200400 | 0.82 | MAPK8 (0.40) | CYP1A2DHODHADORA2AADORA1HTR2B | |
| SCHEMBL18200455 | 0.82 | ADORA2A (0.39) | CYP1A2DHODHADORA2AADORA1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9728731-B2 | Heterocyclic compound and organic light emitting device using same | HEESUNG MATERIAL LTD. (KR) | 2017-08-08 | — | — | US | disclosed |
| US-9728731-B2 | Heterocyclic compound and organic light emitting device using same | HEESUNG MATERIAL LTD. (KR) | 2017-08-08 | — | — | US | disclosed |
| US-20160380208-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME | HEESUNG MATERIAL LTD. (KR) | 2016-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160380208-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME | NOTUM, DDT, CRY1 | CYP1A2 134/4885BACE1 206/4885DHODH 33/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.