Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 3/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | LIG1 | P18858 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18347390 | 0.97 | TP53 (0.44) | TP53CYP4F2CYP4A11PRSS1TMPRSS15 | |
| SCHEMBL18347403 | 0.94 | TP53 (0.46) | TP53CYP4F2CYP4A11PRSS1TMPRSS15 | |
| SCHEMBL18347410 | 0.86 | SMN1; SMN2 (0.47) | DAOALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL18347405 | 0.85 | PRSS1 (0.36) | TP53PRSS1TMPRSS15DAOMRGPRX4 | |
| SCHEMBL18347408 | 0.85 | TP53 (0.36) | TP53PRSS1TMPRSS15DAOMRGPRX4 | |
| SCHEMBL18347395 | 0.84 | SMN1; SMN2 (0.47) | DAOALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL18347401 | 0.83 | MEN1 (0.40) | TP53HPGDALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL18347404 | 0.83 | SMN1; SMN2 (0.36) | TP53PRSS1TMPRSS15DAOMRGPRX4 | |
| SCHEMBL18347387 | 0.83 | TP53 (0.36) | TP53PRSS1TMPRSS15DAOMRGPRX4 | |
| SCHEMBL18347406 | 0.83 | TP53 (0.36) | TP53PRSS1TMPRSS15DAOMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160376248-A1 | METHOD FOR PRODUCING HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE, AND PRODUCTION INTERMEDIATE OF SAME | EA PHARMA CO., LTD. (JP) | 2016-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160376248-A1 | METHOD FOR PRODUCING HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE, AND PRODUCTION INTERMEDIATE OF SAME | CYP4A11, INSR, CYP2C9 | TP53 3651/4885CYP4F2 44/4885CYP4A11 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.