Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | DAO | P14920 | 4/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | LIG1 | P18858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18347390 | 0.94 | TP53 (0.44) | TP53DAOMRGPRX4HPGDMAPT | |
| SCHEMBL18347402 | 0.94 | TP53 (0.44) | TP53DAOMRGPRX4HPGDMAPT | |
| SCHEMBL18347399 | 0.86 | SMN1; SMN2 (0.49) | TP53DAOSMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL18347391 | 0.85 | TP53 (0.38) | TP53DAOMRGPRX4HPGDMAPT | |
| SCHEMBL18347409 | 0.85 | TP53 (0.38) | TP53DAOMRGPRX4HPGDMAPT | |
| SCHEMBL18347400 | 0.82 | SMN1; SMN2 (0.39) | TP53DAOSMN1; SMN2TSHRMAPK1 | |
| SCHEMBL18347410 | 0.81 | SMN1; SMN2 (0.47) | DAOSMN1; SMN2MAPK1NPC1RAB9A | |
| SCHEMBL18347395 | 0.81 | SMN1; SMN2 (0.47) | DAOSMN1; SMN2MAPK1NPC1RAB9A | |
| SCHEMBL18347408 | 0.80 | TP53 (0.36) | TP53DAOMRGPRX4HPGDPKM | |
| SCHEMBL18347405 | 0.80 | PRSS1 (0.36) | TP53DAOMRGPRX4HPGDPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160376248-A1 | METHOD FOR PRODUCING HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE, AND PRODUCTION INTERMEDIATE OF SAME | EA PHARMA CO., LTD. (JP) | 2016-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160376248-A1 | METHOD FOR PRODUCING HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE, AND PRODUCTION INTERMEDIATE OF SAME | CYP4A11, INSR, CYP2C9 | TP53 3651/4885DAO 146/4885MRGPRX4 857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.