Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.50 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18347550 | 0.92 | ESR1 (0.47) | ESR1TSHRSMN1; SMN2LMNACYP1A2 | |
| SCHEMBL15827673 | 0.87 | CHRM2 (0.47) | TSHRSMN1; SMN2LMNAMAPK1L3MBTL1 | |
| SCHEMBL19420345 | 0.82 | ESR1 (0.49) | ESR1TSHRLMNACYP1A2CYP2D6 | |
| SCHEMBL14523149 | 0.82 | NPC1 (0.43) | TSHRSMN1; SMN2LMNAL3MBTL1NPC1 | |
| SCHEMBL12858496 | 0.81 | TRPA1 (0.45) | TSHRSMN1; SMN2LMNAMAPK1L3MBTL1 | |
| SCHEMBL11499291 | 0.79 | SMN1; SMN2 (0.58) | ESR1TSHRSMN1; SMN2LMNACYP1A2 | |
| SCHEMBL4848334 | 0.78 | ALDH1A1 (0.54) | ESR1TSHRSMN1; SMN2LMNACYP1A2 | |
| SCHEMBL16804936 | 0.77 | ESR1 (0.46) | ESR1TSHRLMNACYP1A2CYP2D6 | |
| SCHEMBL388023 | 0.77 | SMN1; SMN2 (0.60) | ESR1TSHRSMN1; SMN2LMNACYP1A2 | |
| SCHEMBL25626561 | 0.77 | SMN1; SMN2 (0.48) | ESR1TSHRSMN1; SMN2LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9864285-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2018-01-09 | — | — | US | disclosed |
| US-20160378000-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2016-12-29 | — | — | US | disclosed |