Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.60 |
| ▸ | NQO2 | P16083 | 6/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23015724 | 0.76 | NQO2 (0.60) | CYP19A1NQO2HTTKDM4ELMNA | |
| SCHEMBL18347811 | 0.72 | CYP19A1 (0.75) | CYP19A1NQO2RXFP1KDM4EALDH1A1 | |
| SCHEMBL18347791 | 0.69 | CYP19A1 (0.68) | CYP19A1NQO2HTTKDM4ELMNA | |
| SCHEMBL5754807 | 0.67 | HTT (0.51) | HTTRXFP1KDM4ELMNAMAPK1 | |
| SCHEMBL21067704 | 0.67 | CYP19A1 (1.00) | CYP19A1NQO2KDM4EALDH1A1HPGD | |
| SCHEMBL16543576 | 0.65 | HTT (0.55) | HTTKDM4EMAPK1ALDH1A1HPGD | |
| SCHEMBL26816560 | 0.65 | HTT (0.58) | HTTRXFP1KDM4ELMNAMAPK1 | |
| SCHEMBL18347795 | 0.64 | CYP19A1 (0.53) | CYP19A1NQO2HTTKDM4EALDH1A1 | |
| SCHEMBL14519905 | 0.64 | KMT2A (0.64) | HTTKDM4ELMNAMAPK1ALDH1A1 | |
| SCHEMBL7439612 | 0.64 | HTT (0.57) | HTTKDM4ELMNAMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10927085-B2 | 1,2-naphthoquinone based derivative and method of preparing the same | HUEN CO., LTD. (KR) | 2021-02-23 | — | — | US | disclosed |
| US-20160376243-A1 | 1,2-NAPHTHOQUINONE BASED DERIVATIVE AND METHOD OF PREPARING THE SAME | KT&G LIFE SCIENCES CORPORATION (KR) | 2016-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10927085-B2 | 1,2-naphthoquinone based derivative and method of preparing the same | UGT1A6, CYP2D6, SLC5A1 | CYP19A1 188/4885NQO2 116/4885HTT 2305/4885 |
| US-20160376243-A1 | 1,2-NAPHTHOQUINONE BASED DERIVATIVE AND METHOD OF PREPARING THE SAME | CYP2S1, SLC5A1, CYP2D6 | CYP19A1 138/4885NQO2 144/4885HTT 1834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.