Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.68 |
| ▸ | NQO2 | P16083 | 6/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18347811 | 0.77 | CYP19A1 (0.75) | CYP19A1NQO2ALDH1A1KDM4EMAPT | |
| SCHEMBL21067704 | 0.71 | CYP19A1 (1.00) | CYP19A1NQO2ALDH1A1KDM4EMAPT | |
| SCHEMBL9348382 | 0.69 | ALDH1A1 (0.53) | ALDH1A1KDM4EMAPTCYP3A4ALOX15 | |
| SCHEMBL18347792 | 0.69 | CYP19A1 (0.60) | CYP19A1NQO2ALDH1A1KDM4EMAPT | |
| SCHEMBL13000074 | 0.68 | ACHE (0.59) | ALDH1A1KDM4EMAPTCYP3A4ALOX15 | |
| SCHEMBL14873828 | 0.68 | CYP19A1 (0.77) | CYP19A1NQO2ALDH1A1KDM4EMAPT | |
| SCHEMBL11251378 | 0.67 | ALDH1A1 (0.55) | ALDH1A1KDM4EMAPTCYP3A4ALOX15 | |
| SCHEMBL3294994 | 0.67 | ALDH1A1 (0.59) | ALDH1A1KDM4EMAPTCYP3A4ALOX15 | |
| SCHEMBL10778338 | 0.66 | ALDH1A1 (0.62) | ALDH1A1KDM4EMAPTCYP3A4ALOX15 | |
| SCHEMBL210330 | 0.66 | ALDH1A1 (0.68) | CYP19A1ALDH1A1KDM4EMAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160376243-A1 | 1,2-NAPHTHOQUINONE BASED DERIVATIVE AND METHOD OF PREPARING THE SAME | KT&G LIFE SCIENCES CORPORATION (KR) | 2016-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160376243-A1 | 1,2-NAPHTHOQUINONE BASED DERIVATIVE AND METHOD OF PREPARING THE SAME | CYP2S1, SLC5A1, CYP2D6 | CYP19A1 138/4885NQO2 144/4885ALDH1A1 628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.