Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GJB2 | P29033 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | GBA1 | P04062 | 5/20 | 0.44 |
| ▸ | IGF2R | P11717 | 4/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24041056 | 0.87 | MAPK1 (0.62) | GJB2MAPK1GBA1 | |
| SCHEMBL15304380 | 0.87 | MAPK1 (0.62) | GJB2MAPK1GBA1 | |
| SCHEMBL19079096 | 0.83 | GJB2 (0.43) | GJB2 | |
| SCHEMBL19079148 | 0.83 | GJB2 (0.43) | GJB2 | |
| SCHEMBL11505730 | 0.81 | GJB2 (0.53) | GJB2MAPK1GBA1IGF2R | |
| SCHEMBL19079099 | 0.81 | GJB2 (0.54) | GJB2MAPK1GBA1 | |
| SCHEMBL22543403 | 0.81 | GJB2 (0.54) | GJB2MAPK1GBA1 | |
| SCHEMBL16221793 | 0.80 | MAPK1 (0.54) | GJB2MAPK1 | |
| SCHEMBL24974871 | 0.80 | MAPK1 (0.54) | GJB2MAPK1 | |
| SCHEMBL15508134 | 0.80 | MAPK1 (0.54) | GJB2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160376585-A1 | OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION | BANK OF AMERICA, N.A. | 2016-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160376585-A1 | OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION | IGF2R, IRS1, INSR | GJB2 4804/4885MAPK1 3890/4885GBA1 125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.