Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27292832 | 0.91 | GAA (0.34) | HDAC1HDAC6SMN1; SMN2GAAHDAC3 | |
| SCHEMBL22959400 | 0.84 | HDAC1 (0.34) | HDAC1HDAC8HDAC6HDAC3 | |
| SCHEMBL22960798 | 0.84 | HDAC1 (0.34) | HDAC1HDAC8HDAC6HDAC3 | |
| SCHEMBL18349843 | 0.80 | HDAC1 (0.45) | HDAC1HDAC8HDAC6SMN1; SMN2GAA | |
| SCHEMBL20233444 | 0.79 | GAA (0.34) | HDAC6GAAALDH1A1KMT2A | |
| SCHEMBL16329615 | 0.79 | — | — | |
| SCHEMBL21431166 | 0.79 | HDAC6 (0.38) | HDAC1HDAC6SMN1; SMN2HDAC3ALDH1A1 | |
| SCHEMBL21431255 | 0.79 | HDAC6 (0.38) | HDAC1HDAC6SMN1; SMN2HDAC3ALDH1A1 | |
| SCHEMBL12191613 | 0.79 | SMN1; SMN2 (0.33) | HDAC6SMN1; SMN2GAAALDH1A1KMT2A | |
| SCHEMBL20371110 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024002924-A2 | FLUORESCENT DYES WITH LARGE STOKES SHIFT | F. HOFFMANN-LA ROCHE AG (CH) | 2024-01-04 | — | — | WO | disclosed |
| US-20160376585-A1 | OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION | BANK OF AMERICA, N.A. | 2016-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160376585-A1 | OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION | IGF2R, IRS1, INSR | HDAC1 2062/4885HDAC8 648/4885HDAC6 935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.