Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18349841 | 0.91 | HDAC1 (0.35) | GAAHDAC6ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL20371110 | 0.81 | — | — | |
| SCHEMBL20233444 | 0.81 | GAA (0.34) | GAAHDAC6ALDH1A1KMT2AKDM4E | |
| SCHEMBL19731703 | 0.80 | HPGD (0.38) | GAAHDAC6ALDH1A1KMT2ACYP3A4 | |
| SCHEMBL4919160 | 0.79 | GAA (0.36) | GAAHDAC6ALDH1A1KMT2AKDM4E | |
| SCHEMBL21431166 | 0.79 | HDAC6 (0.38) | HDAC6ALDH1A1SMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL21431255 | 0.79 | HDAC6 (0.38) | HDAC6ALDH1A1SMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL29929002 | 0.78 | MDM2 (0.32) | KMT2A | |
| SCHEMBL862048 | 0.78 | PBRM1 (0.32) | GAAALDH1A1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL12191613 | 0.77 | SMN1; SMN2 (0.33) | GAAHDAC6ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024002924-A2 | FLUORESCENT DYES WITH LARGE STOKES SHIFT | F. HOFFMANN-LA ROCHE AG (CH) | 2024-01-04 | — | — | WO | disclosed |